Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Radiation Protection > Thyroid > Flashcards

Thyroid Flashcards

1
Q

Thyroid hormones

A

Thyroxine (T4)

Triiodothyronine (T3)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

T4

A

Thyroxine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T3

A

Triiodothyronine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Functions (general) of thyroid hormones

A

metabolic homeostasis

  • affect every tissue
  • protein, lipid, carb metabolism
  • cell differentiation, growth, development
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

NIS

A

sodium iodide symporter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Thyroid regulation

A
  • transport proteins
  • maintain serum levels of thyroglobulin
  • peripheral metabolism by deiodinases
  • metabolism of iodine
  • hypothalamic-pituitary control
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

TSH

A

thyroid stimulating hormone

-stimulates NIS to accumulate iodine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

deiodinases

A

converts T4-T3-T2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

NIS locations

A

thyroid, salivary glands, placenta, brain, lactating breast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T4 potency

A

1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

T4 protein bound

A

10-20

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

T4 half life

A

5-7 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

T4 amount secreted by thyroid

A

80-100 micrograms/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

T3 potency

A

10

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

T3 protein bound

A

1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

T3 half life

A

<24 hours

17
Q

T3 secreted by thyroid

A

6-10 micrograms / day

18
Q

TSH

A

Thyroid stimulating hormone

  • controled by T4 and T3 levels on pituitary
  • levels equate to hypo/hyper
  • euthyroid = normal
19
Q

Thyroid condition prevelance

A

hypothyroidism more prevalent than hyper

20
Q

Hypothyroidism symptoms

A 
fatigue
weight gain
cold intolerance
skin dryness
hair dryness
depression
dementia
cramps
edema
bradycardia
constipation
21
Q

Hyperthyroidism

A 
fatigue
weight loss
heat intolerance
hyperhydrosis
nervousness
insomnia
tremor
weakness
menstrual irregularities
palpitations
hyperdefecation
22
Q

Fetal hypothyroidism

A

low birth weight

congenital cretinism

23
Q

congenital cretinism

A

growth failure
mental retardation
neurodevelopmental delays

24
Q

iodine levels for cretinism

A

<20-25 micrograms /day

25
Q

most common malignant tumor of endocrine system

A

thyroid cancer

26
Q

Thyroid cancer presentation

A
  • painless lump
  • normal function
  • routine exam
  • slow growth
27
Q

Thyroid cancer types

A

Differentiated

Undifferentiated

28
Q

Differentiated thyroid cancers

A

papillary (PTC) - 75-85 %

follicular (FTC) 5-15 %

29
Q

Undifferentiated thyroid cancers

A

Anaplastic Thyroid carcinoma (ATC)

Medullary thyroid carcinoma (MTC)

30
Q

Carcinoma compared to benign nodules

A

Carcinomas only 5%

31
Q

PTC

A

Females 3x more likely and in midlife

32
Q

graves disease

A

most common hyperthyroidism

33
Q

thyroid cancer latency

A

5-7 years

34
Q

Why does it appear thyroid cancer incidence has increased

A

surveillance bias

35
Q

iodine uptake depends on

A
  • percent of administers that enters thyroid
  • size of thyroid
  • bio half life
36
Q

percent administered that enters thyroid depends on

A
  • amount of stable iodine in diet
  • age of patient
  • gland level of function

Radiation Protection (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions