Thymus Flashcards
1
Q
Where is the lympho-epithelial organ located ?
A
anterior to the heart
2
Q
When are thymus fully formed ?
A
functional at birth
3
Q
The involution of the thymus
A
- at the puberty and the lymphatics tissue replaced by adipose tissue
4
Q
Structure of the thymus
A
- poorly developed capsule
- epitheliorecticular cells, few fibers, NO lymphatic nodules
5
Q
Epithelioreticular cells
A
- have junctions and form networks
6
Q
Micro-circulation
A
postcapillary venules, thymus-blood barrier
7
Q
Nurse Cells
A
- thymic epithelial reticular
8
Q
Hassall’s Corpuscle
A
- thymic (medullary epithelioreticular cells )
9
Q
What does the Hassall’s Corpuscle produce ?
A
- produce interleukins in differentiation and education of T-cells
10
Q
DiGeorge Syndrome
A
- the cortical epithelial (epithelioreticular) cell did not develop, thymus is rudimentary
11
Q
What is the consequences of the DiGeorge Syndrome ?
A
- lack of cell-mediated immunity ( low t-cell count)
- loss of parathyroid gland and cardiac abnormalities
