Thromobocytopenia Flashcards
What is thrombocytopenia?
Reduction of platelets to less than 150,000 ul
Acute, severe or prolonged decreases of platelet destruction from normal can result in?
Abnormal hemostasis that presents as prolonged bleeding from minor trauma or spontaneous bleeding without injury
Platelet disorders occur from (3)
Impaired production
Increase destruction
Abnormal distribution
Platelet disorders can be inherited, most are?
Example?
Acquired
Like drugs
Drugs related thrombocytopenia is?
Caused by?
How does it work?
Accelerated platelet destruction
Caused by antibodies
Antibodies Attacking the platelets when the drugs binds to platelets
Many patients with thrombocytopenia are?
Asymptomatic
What is the most common symptom?Examples?
Bleeding
Mucosal or cutaneous
Mucosal bleeding may manifest as? (2)
Nosebleeds
Gingival bleeding
What is bleeding into the skin called?
Petechiae
Petechiae is?
Small flat, red or reddish brown microhemorrhages
When there are many Petechiae we call the resulting reddish skin what?
Purpura
What is the major complication?
Bleeding
Bleeding may be what?
Insidious, acute and internal or external
Where would the bleeding occur? (4)
Body, joints, retina and Brain
Prolonged bleeding from trauma or injury does not occur until platelet counts are under?
50,000