MegaloBlastic anemia Flashcards

1
Q

Megablastic anemia is characterized by?

A

The presence of abnormally large RBC ( macrocyctic )

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Majority Megaloblastic anemia results from deficiency in what (2)?

A

Cobalamin ( vitamin B12 )
Folic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Macrocytic RBC are easily destroyed because they have?

A

Fragile cell membranes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

How is megablastic anemia caused by? And results in?

A

Impaired DNA synthesis
Results in defective RBC maturation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Megablastic anemia can also be from? (3)

A

Congenial disorders

Suppression of DNA synthesis by drugs inborn errors of cobalamin & folic acid metabolism

Erythroleukemia ( cancer blood disorder )

How well did you know this?
1
Not at all
2
3
4
5
Perfectly