MegaloBlastic anemia Flashcards
1
Q
Megablastic anemia is characterized by?
A
The presence of abnormally large RBC ( macrocyctic )
2
Q
Majority Megaloblastic anemia results from deficiency in what (2)?
A
Cobalamin ( vitamin B12 )
Folic acid
3
Q
Macrocytic RBC are easily destroyed because they have?
A
Fragile cell membranes
4
Q
How is megablastic anemia caused by? And results in?
A
Impaired DNA synthesis
Results in defective RBC maturation
5
Q
Megablastic anemia can also be from? (3)
A
Congenial disorders
Suppression of DNA synthesis by drugs inborn errors of cobalamin & folic acid metabolism
Erythroleukemia ( cancer blood disorder )