Thrombosis and Embolism Flashcards
1
Q
What are the 3 components of Virchow’s triad?
A
- Changes in the blood vessel wall
- Changes in the constituents of blood (solid fibrin)
- Changes in the pattern of blood flow
2
Q
Virchow’s triad are factors causing
A
Thrombosis
3
Q
Define thrombosis:
A
Formation of a solid mass from the constituents of blood within the vascular system during life
4
Q
Describe the pathogenesis of thrombosis.
A
- Endothelial injury (e.g due to atheroma)
- Statis or turbulent blood flow
- Hypercoagulability of the blood
(Virchow’s triad)
5
Q
How is hypercholesterolemia related to Virchow’s triad?
A
Causes a change in blood constituents
6
Q
Consequences of thrombosis depend on:
A
- Site
- Extent
- Collateral circulation
7
Q
Outcome of thrombosis:
A
Death or pulmonary embolism