Thrombosis and Embolism Flashcards

1
Q

What are the 3 components of Virchow’s triad?

A
  • Changes in the blood vessel wall
  • Changes in the constituents of blood (solid fibrin)
  • Changes in the pattern of blood flow
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2
Q

Virchow’s triad are factors causing

A

Thrombosis

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3
Q

Define thrombosis:

A

Formation of a solid mass from the constituents of blood within the vascular system during life

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4
Q

Describe the pathogenesis of thrombosis.

A
  • Endothelial injury (e.g due to atheroma)
  • Statis or turbulent blood flow
  • Hypercoagulability of the blood
    (Virchow’s triad)
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5
Q

How is hypercholesterolemia related to Virchow’s triad?

A

Causes a change in blood constituents

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6
Q

Consequences of thrombosis depend on:

A
  • Site
  • Extent
  • Collateral circulation
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7
Q

Outcome of thrombosis:

A

Death or pulmonary embolism

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