Cardiovascular Aetiologies/Risk factors Flashcards

1
Q

Hypertension:

A
Male 
Age 
Smoking 
Diabetes mellitus 
Family history 
Obesity/poor diet/lack of exercise 
Alcohol 
Sleep apnoea 
Race 
Previous MI/stroke 
  • May be primary (90%) or secondary (5-10%) to kidney disease (renal artery stenosis and chronic renal disease) or endocrine disease (Conn’s syndrome, Cushing’s syndrome, phaechromocytoma) and acromegaly)
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2
Q

Atherosclerosis:

A
Male
Age 
Smoking 
Hypertension 
Hyperlipidaemia
Diabetes mellitus 
Family history 
Obesity
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3
Q

Stable Angina:

A
Male
Age 
Smoking 
Hypertension 
Hyperlipidaemia 
Diabetes mellitus 
Obesity 
Family history (of CVD)
Race
Causes: 
Coronary artery atheroma (most common)
Coronary artery spasm 
Arteritis 
Mismatch between supply and demand of oxygen to the myocardium
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4
Q

STEMI

A
Male 
Age
Smoking 
Hypertension 
Hyperlipidaemia 
Diabetes mellitus 
Obesity/lack of exercise/diet 
Family history of ischaemic heaert disease /history of CV disease 
Cocaine use 
Stent thrombosis 
Previous angina = Non-modifiable risk factor
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5
Q

Mitral Stenosis:

A
Congenital MS 
Rheumatic fever 
And 
Prosthetic valve 
Also... rheumatoid arthritis and systemic lupus erythematosus
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6
Q

Mitral Regurgitation:

A

Mitral valve prolapse
Rheumatic fever
Infective endocarditis
Ruptured chord tendineae/dysfunctional papillary muscle
Annular calcification (elderly people)
Connective tissue disorder (e.g Marfan’s syndrome)

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7
Q

Aortic Stenosis

A

Congenital (William’s syndrome, bicuspid aortic valve)
Rheumatic heart disease
And
Sensile calcification

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8
Q

Aortic Regurgitation:

A

Congenital (bicuspid aortic valve)
Rheumatic heart disease
Infective endocarditis
Myxomatous degeneration

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9
Q

Stroke

A
Age
Smoking 
Hypertension 
Hyperlipidemia 
Diabetes mellitus 
Family history 
Obesity/lack of exercise 
Carotid artery stenosis/ carotid artery atherosclerotic plaque rupture  
Atrial fibrillation 
Myocardial infarction
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10
Q

Heart Failure:

A
Age (old)
Smoking 
Hypertension 
Diabetes mellitus 
Valvular heart disease 
Congenital heart defects 
Alcoholism 
HIV
Sarcoidosis 
Restrictive cardiomyopathy
Myocarditis 
Arrythmias 
Ischaemeia/coronary artery disease 
Obstructive sleep apnoea
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11
Q

Atrial fibrillation:

A

Age
Smoking
Hypertension

Heart Failure
Ischaemic heart disease
Valvular disease (mitral regurgitation)

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12
Q

Acute limb ischaemia:

A
Smoking 
HISTORY OF CARDIOVASCULAR DISEASE
Diabetes mellitus 
Atherosclerosis/stenosis 
Coarctation 
Aortic dissection 
Thrombosis 
Trauma 
Vasospasm
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13
Q

Atrial Fibrillation:

A

Age
Smoking
Hypertension

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14
Q

Acute Limb Ischaemia:

A
Smoking 
HISTORY OF CARDIOVASCULAR DISEASE
Diabetes mellitus 
Atherosclerosis/stenosis 
Coarctation 
Aortic dissection 
Thrombosis 
Trauma 
Vasospasm
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15
Q

Chronic Limb Ischaemia:

A
Age 
Smoking 
Hypertension 
Hyperlipidemia 
HISTORY OF CARDIOVASCULAR DISEASE 
Diabetes mellitus 
Beurger’s disease 
Vasculitis
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16
Q

Abdominal Aortic Aneurysm:

A
Male
Age
Smoking 
Hypertension 
Family history

Degenerative disease
Infection (Mycotic aneurysm)
Connective tissue disorder (Marfan’s syndrome)

17
Q

Thoracic Aneurysm:

A
Marfan’s syndrome
Age
Smoking 
Hypertension 
Genetics
18
Q

Aortic Dissection:

A

Marfan’s syndrome
Smoking
Hypetension
Family history

Coarctation
Atherosclerosis
Trauma

19
Q

Dilated Cardiomyopathy:

A
Association with alcoholism and increased BP
Scar replacement 
Haemochromatosis 
Genetic DCM: SCN5A, DMD
Thyrotoxicosis
20
Q

Restrictive Cardiomyopathy:

A
Idiopathic 
Amyloid (infiltrative)
Sarcoid (infiltrative)
Haemochromatosis (storage disease)
Loffler’s eosinophilic endocarditis 
Fibrosis 
Diabetes 
Drugs 
Radiation
21
Q

Hypertrophic Cardiomyopathy:

A

Gene mutation
Idiopathic
Autosomal dominant

22
Q

Myocarditis:

A

Most common cause is viral:

  • Coxsackie B virus
  • Adenovirus
  • Epstein-Barr virus
  • Influenza A and B virus
23
Q

Pericarditis:

A

Vast majority of causes are viral or idiopathic:

  • Coxsackie B virus
  • Echovirus
24
Q

Pericardial Effusion:

A

Often same causes of pericarditis:

  • Coxsackie B virus
  • Echovirus
25
Q

Ventricular Tachycardia:

A
  • Structural heart disease
  • Heart failure
  • Ischaemic heart disease
  • Cardiomyopathy
26
Q

Infective endocarditis:

A

Causes:

  • Streptococcus Viridans (subacute - abnormal valves)
  • Staphylococcus Aureus (acute - normal valves)

Risk Factors:

  • IV track marks
  • Recent dental surgery
  • Diabetes mellitus
  • Rheumatic heart disease
  • Mitral valve disease
  • Renal failure
  • Immunosuppresion