Thrombocytopenia Flashcards
1
Q
Severity
A
mild 100-150K
moderate 50-100K
severe- 50K
2
Q
bleeding risk
A
surgical - < 50K
spontaneous < 20K and mainly < 10K
less bleeding in ITP
3
Q
Thrombocytopenia with thrombosis
A
HIT DIC TTP Vaccine-induced immune thrombotic thrombocytopenia (VITT) APLS PNH
4
Q
PATHOPHYSIOLOGY
A
decreased production- BMF, liver disease (decreased TPO)
destruction- immune, mechanical (TMA)
Hypersplenism- mainly redistribution
