Throat Malignancy Flashcards
Where is the most common site of head and neck cancer
The larynx
What is the most common tumour if the head and neck
Squamous cell carcinoma
Name some factors that have been linked to SSC
Smoking, alcohol, HPV type 16
Name some other types of head and neck cancers
Nasopharyngeal, laryngeal, oropharyngeal and oral cavity carcinoma
Where is nasopharyngeal carcinoma commonly seen
South china
What is nasopharyngeal carcinoma linked to
EBV
What is oropharyngeal cancer commonly associated to in the west
HPV
Where is oral cavity carcinoma commonly seen
South Asia
What has oral cavity carcinoma been linked to
Chewing tobacco
What is the typical patient group for head and neck cancer
Male, >55 with long exposure to smoking and alcohol
Who usually presents with HPV related OP SSC
Non-smoker, higher socio-economic class, multiple sexual partners
How do well differentiated SSC look
Epithelial cells with keratinisation and prickle cells
What is the characteristic spread of supraglottic tumours
drain to superior deep cervical nodes
Where do glottic tumours spread to
Usually stay on the chords (95%)
Where do subglottic tumours spread to
Paratracheal nodes
