Sore Throat Flashcards
What is acute tonsillitis
Inflammation of the tonsils
What does acute tonsillitis frequently occur with
Pharyngitis
What is pharyngitis
Inflammation of the oropharynx
What is the most common cause of tonsillitis and pharyngitis
Viruses
Rhinovirus, influenza, enterovirus etc.
What is the most common bacterial cause of tonsillitis and pharyngitis
Strep pyogenes
Name some other bacterial causes of tonsillitis and pharyngitis
H. Influenza
S. Aureus
Strep pneumo
Name some non-infectious causes of pharyngitis
GORD, chronic irritation from cigarette smoke
Clinical presentation of viral tonsillitis
Malaise, sore throat, temp, able to do normal activity, possibly lymphadenopathy
How long does viral tonsillitis usually last
3-4 days
Clinical presentation of bacterial tonsillitis
Systemic upset, fever, painful swallowing, halitosis, unable to work, lymphadenopathy
What is halitosis
Bad breath
How long does bacterial tonsillitis last
1 week, requires antibiotics to settle
Main scoring system to decide if a patient with tonsillitis needs antibiotics
FeverPAIN
What does FeverPAIN stand for
Fever
Purulence
Attend rapidly (within 3 days)
Inflamed tonsils
No cough
What is the antibiotic prescribed for tonsillitis
Phenoxymethylpenicillin
Antibiotic prescribed for tonsillitis if allergic to penicillin
Clarithromycin
When do you prescribe antibiotics using FeverPAIN
4/5 points
2/3 consider delayed presentation for antibiotics
When to admit or refer a patient with tonsillitis
Difficulty breathing
Neck mass
Persistent symptoms >3 weeks
How is tonsillitis managed in hospital
IV fluids, antibiotics and steroids
Infection control for group A strep infections
Isolate for the first 48 hours of treatment
When is tonsillectomy indicated for adults
Recurrent severe sore throat
Most common complication of tonsillitis
Otitis media
Name some other complications of tonsillitis
Quinsy, parapharyngeal abscess, lemierre syndrome
What is lemierre syndrome
Suppurative thrombophlebitis of jugular vein
Name some late complications of a strep A infection
Rheumatic fever
Glomerulonephritis
ENT symptom of neutropenia
Sore throat
What is diphtheria
Bacterial infection that mainly affects the nose and throat
What causes diphtheria
Corynebacterium diphtheriae
Why does corynebacterium diphtheriae cause you to be ill
Produces a potent exotoxin which is cardiotoxic and neurotoxic
Characteristic symptom of diphtheria
Pseudomembrane across the pharynx
Other symptoms of diphtheria
Malaise, cervical lymphadenopathy, low grade fever
When do symptoms of diphtheria start following infection
2-5 days
Definitive diagnosis of diphtheria
Culture of c.diptheriae from resp tract, secretions or cutaneous lesion
Positive toxin assay
What is used to treat diphtheria
Penicillin, erythromycin
What is used to treat severe diphtheria
Antibiotics + diphtheria antitoxin
What is used to prevent diphtheria
Toxoid vaccine
Progression of neurological toxicity in diphtheria
Local neuropathies
Cranial neuropathies
Peripheral neuritis
Name another complication of diphtheria
Renal failure
What is another name for glandular fever
Infectious mononucleosis
What causes glandular fever
EBV
Pathophysiology of glandular fever
EBV establishes itself in epithelial cells, notably in the pharynx
Clinical presentation of glandular fever
Classic triad of fever, pharyngitis and lymphadenopathy
Clinical signs of glandular fever
Gross tonsillar enlargement with membranous exudates
Cervical lymphadenopathy
Palatal petechial haemorrhages
Rarely hepatosplenomegaly
Blood film in glandular fever
Atypical lymphocytes (activated cytotoxic T lymphocytes)
Investigations for glandular fever
FBC and film
Serology (IgM)
Inflammatory markers
CRP levels in patients with glandular fever
Low
Why do we not prescribe amoxicillin in patients with a sore throat
Generalised macular rash will result
Management of glandular fever
Supportive
Antibiotics to prevent secondary infection
Steroids if severe
Avoid sport for 6 weeks due to risk of splenic rupture
Complications of glandular fever
Anaemia, thrombocytopenia
Splenic rupture
Upper airway obstruction
Increased risk of lymphoma
What causes laryngeal nodes and polyps
Vocal abuse, infection, smoking
What are laryngeal nodes and polyps rarely associated with
Hypothyroidism
Who usually gets pharyngeal nodules
Young women
Where are pharyngeal nodes usually located
Bilaterally on the middle 1/3 to posterior 1/3 of the vocal chord
Where do pharyngeal polyps usually present
Unilaterally
Clinical presentation of laryngeal nodes and polyps
Voice changes: raspy, hoarseness
Pain
Frequent coughing or throat clearing
Management of laryngeal nodes and polyps
May do biopsy
Voice therapy
Some require surgery
What is a contact ulcer
Raw sore on the mucous membrane covering the cartilage to which the vocal chords attach
What causes contact ulcers
Injury to the posterior vocal chord:
Chronic throat clearing, voice abuse, GORD, intubation
Clinical presentation of a contact ulcer
Mild pain while speaking or swallowing
Varying hoarseness
Management of contact ulcers
Rest
Voice therapy
What is another name for a peritonsillar abscess
Quinsy
What is the main cause of quinsy
Secondary to tonsillitis
Pathophysiology of Quincy
Bacteria between the muscle and the tonsil produce puss
Clinical presentation of quinsy
Unilateral throat pain and pain on swallowing
Trismus
Change in voice
Medial displacement of tonsil and vulva
Loss of concavity in palate
When does quinsy usually present
3-7 following acute tonsillitis
Management of quinsy
Aspiration and IV antibiotics
Fluids and analgesia
What is classed as chronic tonsillitis
Symptoms that persist beyond 2 weeks
Clinical presentation of chronic tonsillitis
Chronic sore throat
Bad breath
Presence of tonsillitis
Peritonsillar erythema
Persistent tender cervical lymphadenopathy
Management of chronic tonsillitis
Surgery rarely offered
Dental mouthwash
Should settle by itself
What is epiglottitis
Inflammation of the epiglottis
Common causes of epiglottitis
Strep pneumo, strep pyogenes, staph aureus
Symptoms of epiglottitis
Severe sore throat, drooling saliva, pyrexia
Clinical signs of epiglottitis
No inflammation of tonsils
May have Stridor
Management of mild epiglottitis
Supportive, antibiotics, nebulisers, corticosteroids
Management of severe epiglottitis
Antibiotics, intubation and ventilation, tracheostomy
What is Reinke’s oedema
Swelling of the vocal chords due to fluid collected within the reinkes space
What is the most common cause of Reinke’s oedema
Smoking
Clinical presentation of Reinke’s oedema
Hoarse voice, dysphonia, throat discomfort
What is dysphonia
Abnormal voice changes
Investigation for Reinke’s oedema
Laryngoscopy
Management of Reinke’s oedema
Smoking cessation
Voice therapy
Surgery may be required if symptoms don’t improve