Throat Drugs

Question 1

etiologies of cough

Answer 1

asthma/COPD
GERD
post-nasal drip
ACEI (ace-inhib)

Question 2

classes for cough due to URI

Answer 2

1st gen antihist + decongest
maybe antitussive
not albuterol (unless asthma too)

Question 3

classes for cough due to chronic bronchitis/COPD

Answer 3

ipatropium bromide (atrovent)
codeine + dextomethorphan
not mucolytics

Question 4

antitussive (names)

Answer 4

cough drops
detromethorphan
benzonatate
codeine
lidocaine

Question 5

dextromethorphan hydrobromide class

Answer 5

antitissuve

Question 6

dextromethorphan hydrobromide MOA

Answer 6

NMDA receptor antag:
anesthetic
opioid-like
cross BBB

Question 7

dextromethorphan hydrobromide CI

Answer 7

MAOIs

pts with Na restriction

Question 8

dextromethorphan hydrobromide ADRs

Answer 8

dissociative properties (hallucinogenic)
"club drug"

Question 9

codeine class

Answer 9

antitussive

Question 10

codeine MOA

Answer 10

opioid agonist (at mu receptor)

Question 11

codeine ADRs

Answer 11

same as opiods:
respiratory depresion
HA
dizziness
tachy/palpitations
rash/itch
N/V

Question 12

benzonatate class

Answer 12

antitussive

Question 13

bensonatate MOA

Answer 13

anesthetize stretch receptor in lung, respir passage, and pleura –> reduced cough reflex

Question 14

benzonatate ADRs

Answer 14

preg class C
sedation
dizziness
HA
hallucination
GI upset

Question 15

guaifenesin class

Answer 15

mucolytic/expectorant

Question 16

guafenesin MOA

Answer 16

increase respiratory fluid, thin secretions

may impair normal inflammatory response to URI

Question 17

guafenesin ADRs

Answer 17

N/V

drowsy