Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharm > antiparasites > Flashcards

antiparasites Flashcards

1
Q

malaria drugs (names)

A 
chloroquine
atovaquone-proguanil
artemisinins
primaquine
quinine
mefloquine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

chloroquine indication

A

first line for malaria

good for peds and preg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

chloroquine ADRs

A

N/V/D/pn
HA
blurry vision
itching (give benadryl with it)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

atovaquone-proguanil indication

A

first line malaria tx in CQ-reist

also tx PJP/PCP pneumo in SMX-DXP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

atovaquone-proguanil ADRs

A

N/V/C/pn (if too much N/V/ and cant keep down –> doesnt work)
HA
rash (might ned to stop med)
elevate LFT temporarily

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

atovaquone-proguanil drug interactions

A

rifampin (increase)

tetracycline (reduce)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

artemisinins (names)

A

artemether
artesunate
artemisin combo therapy (ACT)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

artemisinins indications

A

first line for WHO

alt option for CDC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

artemisinins ADRs

A

neuro effects (in animal studies)
some liver/neutrophil probs
hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

primaquine MOA

A

acts in liver stage– the only one

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

primaquine indications

A

PEP (post exposure prophylaxis) of malaria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

primaquine CI

A

G6PD deficiency

preg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

quinine indication

A

anti malarial

off-label for leg cramps (but doesnt work…)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

quinine ADRs

A 
cinchonism (tinnitus, vision prob, HA, dysphoria, N/V, hypotension)
low BGL
low BP
GI
CV: long QT
skin probs
antag myastehnia gravis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

mefloquine indication

A

prophylax against CQ-resist p. falcirum

NOT a tx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

mefloquine ADRs

A

neuro
cardiac
kids vomit

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

mefloquine CI

A

preg

kids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

antileishmaniasis (name)

A

miltefosine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

miltefosine indication

A

leishmaniasis

20
Q

miltefosine ADRs

A 
N/V/D
HA
decrease appetite
dizzy
itching
drowsy
elevate LFT and creatinine
21
Q

miltefosine CI

A

pregnancy (and don’t get preg 4 mo following completion)

22
Q

anti-ameoba azoles (names)

A

metronidazole

tinidazole

23
Q

ameoba azole MOA

A

form free radicals inside microbial cells –> death

24
Q

metronidazole indication

A 
c. diff
trichomoniasis
serious anaerobe infect (and, SSTI, sepsis)
rosacea
h/ pylori
vaginitis
25
Q

metronidazole ADRs

A 
CNS (rare) sz, encephalopathy, meningitis
liver probs (esp in old ppl)
GI: N/V/D/pn
HA
anorexia
dysguesia
black hairy tongue
leukopenia
candidiasis
26
Q

metronidazole drug interactions

A

ETOH/disulfuram rxn
warfarin/Li (increase)
phenobarbitol (decrease)

27
Q

metronidazole CI

A

first trimester preg

28
Q

tinidazole indications

A

trichominiasis
bact vaginosis
giardasis
H. pylori (off label)

29
Q

tinidazole ADRs

A

metallic taste
nausea
weak/fatigue

30
Q

paromomycin indication

A

water-borne parasites
2nd line for lots of things (amebiasos, cryptosporid, giardiasis)
adjunct or hepatic coma

31
Q

paromomycin CI

A

intestinal obstruction

32
Q

paromomycin ADRs

A

N/D/cramps (with bigger dose)

33
Q

antihelminth (names)

A

mebendazole
albendazole
praziquantel

34
Q

mebendazole MOA

A

prevent gluc uptake

block mucrotubules when trying to grow

35
Q

mebendazole indication

A

all the worms: hook, pin, round, whip

maybe even tape worm

36
Q

mebendazole ADRs

A 
monitor liver fnx
and pn, diarhea
rash, urticaria
angioedema
sz, hepatitis (rare)
37
Q

mebendazole CI

A

preg cat C

38
Q

albendazole MOA

A

inhibit microtubule formation

39
Q

albendazole inidcation

A

tapeworm

hookworm (off label)

40
Q

albendazole ADRs

A 
N/V/D/pn
HA
vertigo
alopecia
fever
elevate LFT
pancytopenia (worse with liver dz, bone marrow suppression)
41
Q

albendazole CI

A

preg cat C

42
Q

albendazole drug interactions

A

dexmethasone (increase)

praziquantel (increase)

43
Q

praziquantel MOA

A

affect parasite cell mem perm

cysticidal

44
Q

praziquantel indication

A

DOC for schistosomiasis (caused from cystericercosis)

45
Q

praziqauntel CI

A

rifampin

46
Q

praziquantel caution

A

P450 3A4 metabolite

Pharm (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions