Third Week of Development Flashcards

1
Q

Characteristics of the third week

A

Formation of germ ayers, early tissue, orga differentiation

  • coincides with the first missed menstrual period
  • Includes the formation of the primitive streak, notochord, neural tube, somites
  • Beginning of the embryonic period
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2
Q

When does the embryonic period begin

A

Week 3

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3
Q

Gastrulation

A

Process by which the bilaminar embryonic disc is converted to a trilaminar embryonic disc

  • Occurs via. the formation of the primitive streak
  • Cells of epiblast origin migrate down the prmitive groove to establish the intraembryonic mesoderm and endoderm
  • Epiblast is renamed ectoderm
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4
Q

What are the trilaminar layers

A

Intraembryonic mesoderm, intraembryonic endoderm, hypoblast

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5
Q

Notochord

A
  • axis for the development of the axial skeleton
  • induces the formation of the bodies of the vertebrae
  • Part persists as the nucleus pulposus of the intervertebrae discs
  • induces the overlying ectoderm to form the neural plate
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6
Q

When does neural tube formation occur

A

Begins in the 3rd week, completes by the end of the 4th

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7
Q

Neurulation

A
  • Neural tube formation
  • ectoderm thickens to form the neural plate
  • Day 18: neural plate invaginates to form the neural groove and neural folds on either side
  • End of 3rd week: neural folds fuse, converting the neural groove into the neural tube
  • Anterior neuropore closes day 25
  • Posterior neuropore closes day 27
  • Neural c5rest cells form from margins of folds
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8
Q

When does the anterior neuropore close

A

Day 25

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9
Q

When does the posterior neuropore close

A

Day 27

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10
Q

What occurs when neural tubes are open

A

Amniotic fluid flows through

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11
Q

Development of the Somites

A
  • Paraxial mesoderm forms paired, cube-shaped blocks (somites)
  • Occurs days 20-38
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12
Q

What do somites give rise to

A
  • Vertebrae (sclerotomes)
  • Muscles of neck, body wall, limbs (myotomes)
  • Dermis of scalp, neck, trunk (dermatomes)
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13
Q

Development of the intraembryonic coelom

A
  • Spaces appear in the lateral mesoderm and coaslesce to form the intraembryonic coelom
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14
Q

Intraembryonic coelom

A

Divides into intraembryonic splanchnic mesoderm and intraembryonic somatic mesoderm
- gives rise to the pericardial, pleural, and peritoneal cavities

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15
Q

Intraembryonic splanchnic mesoderm

A

forms the gut wall with the endoderm, derived from the intraembryonic coelom

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16
Q

Intraembryonic somatic mesoderm

A

Forms the body wall with the ectoderm, derived from the intraembryonic coelom

17
Q

What forms the somatopleure

A

(gut wall)

- Intraembryonic splanchnic mesoderm and the endoderm

18
Q

What forms the splanchnopleure

A

(body wall)

- Intraembryonic somatic mesoderm and the ectoderm

19
Q

Pericardial cavity

A

Derived from the intraembryonic coelom, gives rise to the heart

20
Q

Pleural cavity

A

Derived from the intraembryonic coelom, gives rise to the lungs

21
Q

Peritoneal cavity

A

Derived from the intraembryonic coelom, gives rise to the gut

22
Q

Vasculogenesis

A

Formation of new vascular channels by assembly of individual cell precursors (angioblasts)

23
Q

Angiogenesis

A

Formation of new vessels by budding and branching from preexisting vessels

24
Q

What is the first functional system

A

cardiovascular system

25
Q

How are secondary villi formed

A

in week 3, mesoderm grows into the primary villi, converting them to secondary villi

26
Q

How are tertiary villi formed

A

mesoderm differentiates to form blood vessels, converting secondary villi to tertiary villi