Nervous System Flashcards
3 parts of the nervous system
Central, peripheral, autonomic
Nervous system parts
Central, peripheral, autonomic
CNS
Central nervous system, includes the bran and spinal cord
PNS
Peripheral nervous system, includes neurons outside the CNS and cranial and spinal nerves that connect the bran and spinal cord with peripheral structures
ANS
Autonomic nervous system, includes parts in both the CNS & PNS and consists of neurons that innervate smooth muscle, cardiac muscle, glandular epithelium
What does the neural tube differentiate into
CNS
Origin of the nervous system
Develpoes from the neural plate, notochord and paraxial mesenchyme induce the overlying ectoderm to differentiate the neural plate
Nervous system signalling molecules
TGFB famly, SHH, BMPs
Prmary bran vescles
Forebrain, midbrain, hindbrain
Prosencephalon
Forebrain
Mesencephalon
Mid brain
Rhombencephalon
Hind brain
Secondary brain vesicles
Telecephalon, diencephalon, mesencephalon, metencephalon, myelencephalon
Adult derivatives of secondary brain vesicles
Cerebrum, thalami, midbrain, pons, cerebellum, medulla
Cervical flexure
demarcates the hindbrain from the spinal cord
Pontine flexure
divides the hindbrain into caudal and rostral
Medulla regions
caudal closed and rostral open
What occurs when the myelencephalon migrate into the marginal zone
Isolated areas of grey matter are formed - gracile nuclei and cuneate nuclei
What do the neuroblasts of the alar plate form
Discrete nuclei
Four columns of neuroblasts in the alar plate
Medial - Lateral:
General visceral afferent, special visceral afferent, general somatic afferent, special somatic afferent
General somatic afferent
Receives impulses from the surface of the head
Special somatic afferent
Receives impulses from the ear
General visceral afferent
Receives impulses from the viscera
Special visceral afferent
Receives taste fibres
Three columns of neuroblasts in the basal plates
Medial - Lateral:
General somatic efferent, special visceral efferent, general visceral efferent
General somatic efferent
Represented by neutrons of the hypoglossal nerve
Special visceral efferent
Represented by neutrons inner sting muscles derived from the pharyngeal arches
General visceral efferent
Represented by some neurons of the vagus and glosses - pharyngeal nerves
Pia matter
Covers the thin ependymal roof of the fourth ventricle
Tela Choroidea
Formed b the pia matter and teh ependymal roof of the fourth ventricle
Why does the tela choroidea invaginate
Rapid proliferation of the pia matter
Choroid plexus derivative
Vascular fluid, which becomes CSF
Superior and inferior colliculi
Formed by the neuroblasts of the alar plate, involved in visual and auditory reflexes
Cerebral penduncles
Ventral aspect of the nuclei formed by the neuroblasts of the basal plate, They’re fibre tracts from the cerebrum
Neural canal derivative (mesencephalon)
Cerebral aqueduct
Neural canal derivative (diencephalon)
Third ventricle
Where does the pituitary gland develop from
Hypophysial diverticulum and neurohypophysial diverticulum
Cerebral vesicles
Bubble-like outgrowths of the cranial forebrain, become the left and right cerebral hemispheres
Neural Canal derivative (telencephalon)
Lateral ventricles
Cerebral cortex
Formed by the migration of cells of the intermediate layer to the marginal layer
Neurulation
Formation of the tube and plate, begins in week 3
Microepithelial cell derivatives
Neuroblasts, glioblasts, ependymal cells
3 layers of neural tube wall
Inner ventricular, intermediate, outer marginal
Ventricular layer
Hosts ependymal cells
Intermediate layer
Hosts neuroblasts and glioblasts
Marginal zone
Outer part of neural, also glial zones
What does the spinal cord develop from
Neural tube caudal to the fourth pair of somites
When does the central canal appear
9/10 weeks
Sulcus limitans
Separates side walls into dorsal alar plates and ventral basal plates
Alar plate derivative
Horns of grey matter
Marginal layer derivative
White matter
What are the unipolar neurons in spinal ganglia derived from
Neural crest cells
Basal plate derivatives
Lateral and ventral horns of grey matter
Are basal efferent or afferent
Efferent
Are alar efferent or afferent
Afferent
What do the axons in neurons in the ventral horn become
Form the ventral roots of spinal nerves
Dorsal primary rami
Innervate the limbs, vertebral joints, and the skin of the back
Ventral primary rami
Innervate the libs and ventral body wall
Spinal nerve division
Divides into the dorsal and ventral primary rami
Primordial meninx
Formed from the mesenchymal surrounding the neural tube
Dura matter
Thickened external layer of the spinal meninx
Pia-arachnoid
Inner layer of the spinal meninx, composed of pia matter and arachnoid matter, derived from neural crest cells
Cerebrospinal fluid
Begins to form in week 5 from vascular fluid
Why does the spinal cord change position
The vertebral column grows more rapidly than the spinal cord
Positional changes of the spinal cord
Spinal cord moves to progressively higher levels within the vertebral column, ends at L1 in adults
Myelination of nerve fibres
Begins in late fetal period and continues during first year after birth
Schwann cells
From neural crest cells, form myelin in PNS
Oligodendrocytes
Form myelin in CNS
When do tracts become functional
Upon myelination