Things always forget Flashcards

1
Q

Xeroderma pigmentosum is caused by a failure in…

A

Nucleotide excision repair (NTER)

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2
Q

NTER is the major failure in which disorder?

A

Xeroderma pigmentosum

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3
Q

Hereditary non-polyposis colorectal cancer is caused by a failure in…

A

Mismatch excision repair (MER)

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4
Q

Mismatch excision repair (MER) is the major failure in which disorder?

A

Hereditary non-polyposis colorectal cancer

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5
Q

Cockayne disease is caused by a failure in…

A

Transcription coupled repair

*in ERC6/8

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6
Q

Failure in transcription coupled repair is the major cause of which disease?

A

Cockayne disease

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7
Q

BRCA disorders are caused by a failure in…

A

Homologous recombination

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8
Q

Failure in homologous recombination are the major cause of….

A

BRCA

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9
Q

What does DNA pol utilize to fix?

A

BER

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10
Q

Direct repair fixes what?

A

Pyrimidine dimers

O6 methyl guan.

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11
Q

Base excision repair: how does it work?

A

Fix one wrong nt., detect via DNA glycosylase

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12
Q

What does Nucleotide excision repair fix?

A
  • Steric hinderance

- Remove damaged chunk DNA

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13
Q

What does Mismatch excision repair fix?

A

Daughter strand in replication

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