Things always forget Flashcards
Xeroderma pigmentosum is caused by a failure in…
Nucleotide excision repair (NTER)
NTER is the major failure in which disorder?
Xeroderma pigmentosum
Hereditary non-polyposis colorectal cancer is caused by a failure in…
Mismatch excision repair (MER)
Mismatch excision repair (MER) is the major failure in which disorder?
Hereditary non-polyposis colorectal cancer
Cockayne disease is caused by a failure in…
Transcription coupled repair
*in ERC6/8
Failure in transcription coupled repair is the major cause of which disease?
Cockayne disease
BRCA disorders are caused by a failure in…
Homologous recombination
Failure in homologous recombination are the major cause of….
BRCA
What does DNA pol utilize to fix?
BER
Direct repair fixes what?
Pyrimidine dimers
O6 methyl guan.
Base excision repair: how does it work?
Fix one wrong nt., detect via DNA glycosylase
What does Nucleotide excision repair fix?
- Steric hinderance
- Remove damaged chunk DNA
What does Mismatch excision repair fix?
Daughter strand in replication