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Drugs > Thiazolidinediones (TZDs, glitazones) > Flashcards

Thiazolidinediones (TZDs, glitazones) Flashcards

1
Q

Mechanism

A

Ligands to PPAR-gamma
Increase insulin sensitivity

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2
Q

Glucose dependant or independent

A

Glucose independent

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3
Q

Clinical use

A

Decreases blood glucose (increases insulin sensitivity)

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4
Q

Name some drugs

A

Pioglitazone etc

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5
Q

Side effects

A

Increase weight, increase fracture risk, mild anaemia, fluid retention

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6
Q

When not to use

A

If they have heart problems

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Drugs (10 decks)

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