DPP-4 inhibitors (gliptins) Flashcards

1
Q

Mechanism

A

Inhibit DPP-4 to prolong actions of GLP-1 and GIP

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2
Q

Clinical use

A

Decreases blood glucose (increase insulin, decreases glucagon)
Decreases BP
No effect on weight

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3
Q

Name some drugs

A

Sitagliptin etc

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4
Q

Side effects

A

Nausea, increase risk of pancreatitis

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5
Q

Glucose dependant or independent

A

glucose dependent

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