Thermoregulation Flashcards

1
Q

What is a homeotherm?

A

An organism which maintains a constant internal temperature regardless of the external influence

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2
Q

What is a poikilotherm?

A

An organism whose internal temperature changes with ambient temperature

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3
Q

What is heat a result of?

A

A by-product of metabolism

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4
Q

How do homeothermic animals regulate a constant internal temperature?

A

Regulate rate of heat produced and heat loss to control the overall body temperature

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5
Q

There are limits to thermoregulatory mechanisms and two issues can arise if the temperature is too high or too low, what are these?

A

Too high - hyperthermia

Too low - hypothermia

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6
Q

What is hypothermia?

A

Abnormally low body temperature

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7
Q

What is hyperthermia?

A

Dangerously high body temperature

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8
Q

Why is thermoregulation important?

A

For cellular function - homeostasis ensures optimal temperature for cellular metabolism

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9
Q

What is the normal body temperature?

A

37 degrees

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10
Q

List five factors which would affect the normal body temperature

A
  1. diurnal variation
  2. menstrual cycle
  3. exercise
  4. age
  5. ambient temperature
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11
Q

What is diurnal variation?

A

the variation between a high temperature and a low temperature that occurs during the same day

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12
Q

At what temperatures would you die? Max and min please lol

A

max would be 43ish and min would be 26 degrees

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13
Q

What occurs when the the body overheats?

A

Nerve malfunction and protein denaturation

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14
Q

At what temperature would there be body convulsions?

A

41 degrees

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15
Q

What temperature is the upper limit compatible with life?

A

43.3 degrees

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16
Q

What occurs when the body cools?

A

The metabolic activity decreases but the tissues may withstand transient substantial cooling

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17
Q

Overheating is considered more serious than cooling, true or false?

A

True

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18
Q

The body temperature differs between which two regions?

A

The core body temperature differs from the shell temperature

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19
Q

What is included in the core body temperature? Which regions?

A

The CNS, abdominal and thoracic cavities

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20
Q

How would you describe the temperature regulation and general temperature of the core regions?

A

Precisely regulated and the highest temperature between the to, roughly 37.8 degrees

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21
Q

What regions are included within the shell temperature|?

A

Skin and subcutaneous fat, and basically the outer parts lol

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22
Q

What temperature range does the shell temperature fluctuate between?

A

Around 20 degrees to 40 degrees

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23
Q

How is heat exchanged between the core and the shell regions of the body?

A

By blood homie x

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24
Q

What is required for the heat in the body to be balanced, this is basically a btec question.

A

The heat input must equal the heat output

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25
Where may you gain heat from?
Internal heat production and the external environment
26
Where may you lose heat to?
To the environment
27
If the heat input and heat output is not equal, we have a disruption of the
HEAT BALANCE (btec question once again, sorry)
28
What are the four mechanisms of heat transfer?
Radiation, conduction, convection and evaporation
29
Describe what radiation is?
The emission of heat energy from the surface of a warm body via em waves
30
If the skin temperature is greater than the environmental temperature what occurs via radiation?
Heat is lost to the surroundings - so it cools the bod down a bit basically
31
Describe what the mechanism of heat transfer conduction involves?
The transfer of heat between two objects in direct contact
32
What two factors does heat transfer via conduction depend on?
On the temperature difference and the conductivity of the objects
33
Describe the process of convection
It is the transfer of heat by air/ water currents. The heat is conducted to the air immediately next to the skin
34
What is a convection current?
Warm air rises and is replaced by cool air,
35
On what kind of day would you expect more heat loss by convection currents?
On a windy day
36
What is evaporation?
The conversion of water from a liquid form to a gas form
37
Why does evaporation cool the body down?
Because it requires thermal energy which is absorbed from the skin which obvs cools down the body
38
How would you describe the process of insensible water loss by evaporation?
It is a continuous (passive) process
39
How can water be lost 'insensibly', under the category of insensible loss?
Respiratory airways (air is humidified) and the skin
40
What nervous system regulates sensible loss?
The sympathetic nervous system
41
Sensible water loss includes what process by which glands?
Sweating by eccrine sweat glands
42
How much water would you normally expect to lose per day?
100 ml a day
43
How much water would you expect to lose on a hot day?
1.5 litres a day
44
How much water would you expect to lose with vigorous exercise?
4 litres per day
45
What is the humidity?
The amount of water vapour present in the air
46
If the relative humidity is high, this means the air is almost fully saturated with h2o, how would this affect the body in terms of thermoregulation?
There would be limited evaporative heat loss
47
Which two ways does the body get heat input internally?
Oxidation of fuel and utilisation of ATP
48
How efficient is oxidation of fuel, and how efficient is the utilisation of ATP?
50% efficiency for the oxidation of fuel and 25% efficiency for the utilisation of ATP
49
How does the body get heat input externally?
From the environment
50
How does the body lose heat?
Externally, by radiation, conduction and convection
51
How much of heat is lost by radiation?
50%
52
How much of heat is lost by conduction?
A small amount
53
How much heat is lost by convection?
A significant amount
54
What is the only mechanism of heat loss on a hot day?
By evaporation depending on relative humidity
55
What is the thermoregulatory integrating centre?
The hypothalamus
56
What is the posterior region of the hypothalamus activated by?
By the cold
57
What is the anterior region of the hypothalamus activated by?
By the heat
58
How do thermoreceptors work?
They get afferent input to the hypothalamus
59
There are central and peripheral thermoreceptors, what are they?
The central would be the brain, spinal cord and internal organs, the peripheral would be the skin
60
What is the aim of the skin vasomotor responses?
To alter the temperature gradient between the skin and the environment
61
The radius of blood vessels determines what?
The blood flow obviously
62
Blood flow can very between which ranges per minute?
400-2500ml/min
63
Which sub division of the sympathetic nervous system is involved in vasoconstriction and vasodilation?
The sympathetic nervous system
64
Describe vasoconstriction
There is a smaller diameter, greater resistance, lower blood flow, lower skin temp, lower conductive and radiative heat loss, conserves heat
65
Describe vasodilation
Greater diameter, lower resistance, greater blood flow, higher skin temp, higher conductive and radiative heat loss
66
What does shivering do when you are cold as a method of heat conservation and heat producing?
Shivering is heat producing as obvs the skeletal muscles move
67
What are the three effectors involved in thermoregulation?
1. Peripheral blood vessels 2. Sweat glands – eccrine 3. Skeletal muscles
68
How does the effector the peripheral blood vessels respond
Peripheral blood vessels • vasoconstriction / vasodilation alters BF to skin • >> control conductive & radiative heat loss
69
How does the effector, the sweat glands respond
Sweat glands - eccrine • control evaporative heat loss • sweat production (sympathetic control)
70
How does the effector the skeletal muscles respond?
Shivering - increase in muscle tone • rapid involuntary rhythmic contractions (10-20/sec) • ALL energy liberated is converted to heat • 2-5 fold increase in heat within secs/mins
71
Changes in skin temperature are monitored by what?
By peripheral thermoreceptors in the skin
72
Changes in the core temperature is monitored by what?
By central thermoreceptors in the hypothalamus, abdominal organs,
73
Define fever
The elevation of blood temperature as a result of infection/inflammation
74
What triggers fever?
Infection or inflammation
75
What happens to white blood cells when one has fever?
They proliferate and secrete chemical substances
76
What are the chemical substances that while blood cells release when one has fever?
Endogenous pyrogens - fever inducers
77
What do endogenous pyrogens stimulate the release of?
Of prostaglandins
78
What effect do prostaglandins have on the body?
They increase the hypothalamic set point
79
What is the effect of the increasing of the set temperature by the hypothalamus?
The body thinks its too cold, involuntary and voluntary heat production mechanisms begin
80
What is a common symptom of the onset of fever?
Feeling cold
81
Fever is an intentional response of the body and not a failure of the thermoregulatory system, why?
A higher temperature augments the immune response
82
What is the most common cause of hypothermia?
Exercise
83
Explain how exercise induced hypothermia takes place
As a physical consequence of the tremendous heat load generated by exercising muscles, body temperature begins to rise during the initial stage, stabilises, and then maintained at a higher level during exercise several degrees above resting set point
84
Explain how hyperthermia can occur pathologically?
Due to dysfunction of the thyroid gland, medulla or brain lesions
85
How can hyperthyroidism caused hyperthermia?
An increase of thyroid hormone, an increased basal metabolic rate, increased heat production
86
How does aspirin act to break a fever?
Aspirin reduces a fever by inhibiting the synthesis of prostaglandins
87
Why does aspirin not lower the temperature in a non febrile individual?
In the absence of endogenous pyrogen, prostaglandins are not present in the hypothalamus in appreciable quanitites