Sensory Systems part 2 Flashcards

1
Q

Most cells can sense chemical stimuli, what is this called?

A

Chemoreception

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2
Q

Animals have many types of chemoreceptors, give examples of two

A

Olfaction and gustation

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3
Q

What is olfaction?

A

Smell - the detection of chemicals in the air

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4
Q

What is gustation?

A

Taste - detection of chemicals emitted from food

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5
Q

What three structural criteria distinguish olfaction and gustation?

A
  1. performed by different sense organs
  2. different signal transduction mechanisms
  3. processed in different integrating centres
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6
Q

What type of receptors does the olfactory system contain?

A

Odorant receptors

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7
Q

Binding of an odorant to an odorant receptor causes what?

A

A conformational change

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8
Q

What happens once a odorant binds to an odorant receptor causing a conformational change?

A

A G protein is activated, G-olf. It then moves through the membrane and activates the enzyme adenylate cyclase

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9
Q

What does the enzyme adenyl cyclase convert into what?

A

It converts ATP into cAMP

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10
Q

What is the purpose of cAMP in the olfactory system response?

A

cAMP opens cAMP gated ion channels

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11
Q

Once cAMP gated channels are opened, what two ions can enter the cell causing a generator potential?

A

Ca2+ and Na+

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12
Q

How do Cl- ions leave the cell and cause depolarisation?

A

The Ca2+ ions that enter the cell opens ca2+ activated cl- channels, causing cl- to leave the cell, increasing the depolarisation

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13
Q

How are action potentials finally triggered by the olfactory system?

A

The generator potential opens the voltage gated na+ channels, triggering action potentials

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14
Q

The gustatory system consists of five classes of tastants, what are these?

A

Salty, sweet, bitter, sour and umami

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15
Q

What do sweet, umami and salty tastes indicate?

A

Carbohydrates, proteins and ions

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16
Q

What do bitter and sour tastes indicate?

A

Potentially toxic substances

17
Q

*Label this vertebrate taste bud

A

There

18
Q

Taste receptor transduction pathways vary for

A

The different tastes, salty, sour, sweet, bitter

19
Q

In the salty taste receptor transduction pathway what happens?

A

The Na+ from salty food enters through a Na+ channel
The resulting depolarisation opens voltage gated Ca2+ channels
The influx of Ca2+ causes neurotransmitter release

20
Q

What happens in the sour taste receptor pathway?

A

H+ ions from sour foods block the K+ channel
This blockage prevents K+ from leaving the cell
The resulting depolarisation opens voltage gated ca2+ channels
The influx of Ca2+ causes neurotransmitter release

21
Q

What happens in the sweet taste receptor transduction pathway?

A

A sweet substance binds to its receptor causing a conformational change
The activated G protein, gustducin activates adenylate cyclase
Adenylate cyclase catalyses the conversion of ATP to cAMP
The cAMP activates a protein kinase that phosphorylates and closes a K+ channel
The resulting depolarisation opens voltage gated ca2+ channels
The influx of Ca2+ causes neurotransmitter release

22
Q

What happens in the bitter taste receptor transduction pathway?

A

A bitter substance binds to its receptor, causing a conformational change
The activated g protein, transducin activates phospholipase c
PLC catalyses the conversion of PIP2 into the second messenger IP3
IP3 causes the release of Ca2+ from intracellular stores
The influx of Ca2+ causes neurotransmitter release