Reproduction Flashcards

1
Q

What are the three main parts making up the reproductive system

A

the gonads, the reproductive tract and the accessory sex glands

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2
Q

what is a reproductive tract

A

ducts that transport/house gametes

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3
Q

what are accessory sex glands

A

supportive secretions for gametes

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4
Q

what are primary reproductive organs and how do they exist

A

gonads and they exist in pairs

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5
Q

what are the two functions of the gonads

A

to produce gametes by gametogenesis and to secrete sex hormones

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6
Q

what are the male gonads called

A

the testes

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7
Q

what is the function of the male gonads called the testes

A

to produce sperm and androgens

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8
Q

what are the female gonads called

A

the ovaries

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9
Q

what is the function of the female gonads

A

to produce ova, oestrogen and progesterone

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10
Q

name a organ other than the gonads that also produces sex hormones

A

the adrenal gland- the cortex part

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11
Q

what sex hormone does the adrenal gland produce

A

dehydroepiandostrone (dhea)

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12
Q

what are all steroid hormones derived from

A

from cholesterol

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13
Q

how are steroid hormones produced

A

through a series of enzymatic reactions

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14
Q

each steroidogenic organ has specific enzymes in order to produce

A

specific hormones

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15
Q

the male hormone testosterone can have both reproductive and non reproductive actions, list three reproductive actions of testosterone

A

secondary sexual characteristics, growth and maturation of the system and spermatogenesis

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16
Q

the male hormone testosterone can have both reproductive and non reproductive actions, list three non reproductive actions of testosterone

A

libido at puberty, protein anabolic effect and bone growth at puberty

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17
Q

what are the two female gonadal hormones

A

oestrogen and progesterone

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18
Q

the female gonadal hormones can have both reproductive and non-reproductive actions, list five reproductive actions of the female gonadal hormones

A

secondary sexual characteristics, growth and maintenance of the reproductive tract, oogenesis, specific actions during pregnancy and parturition

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19
Q

the female gonadal hormones can have both reproductive and non reproductive actions, list two non reproductive actions of the female gonadal hormones

A

increase in fat deposition and an increase in bone density

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20
Q

what controls the secretion of the gonadal hormones

A

fsh and lh

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21
Q

what does the follicle stimulating hormone do in females

A

ovarian follicular development and oestrogen secretion

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22
Q

what does the follicle stimulating hormone play a role in in males

A

sperm production

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23
Q

what is lh involved in in females (3 points)

A

ovulation, luteinization and the secretion of oestrogen and progesterone

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24
Q

what is lh involved in in males

A

testosterone secretion

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25
where is the location of the testes
in the scrotum, outside of the body, cooler temperature ideal for spermatogenesis
26
what is the role of the seminiferous tubules
the site of sperm production via spermatogenesis
27
where are the sertoli cells found
within the seminiferous tubules in the testes
28
what is the function of the sertoli cells
to support sperm development
29
what hormone do sertoli cells secrete and what is the role of this hormone
they secrete inhibin which inhibits FSH
30
where are leydig cells found
between the seminiferous tubules within the testes
31
what is the function of the leydig cells
to secrete testosterone stimulated by lh
32
what is the role of lutenising hormone in spermatogenesis
lh stimulates testosterone secretion, testosterone stimulates spermatogenesis
33
what is the role of fsh in spermatogenesis
fsh stimualtes spermatogenesis
34
what does testosterone do in spermatogenesis exactly
testosterone stimulates mitotic and meiotic divisions, you get undifferentiated diploid germ cells called spermatogonia and undifferentiated haploid spermatids
35
what does fsh do in spermatogenesis exactly
remodels spermatids to highly specialised motile spermatozoa
36
how long does the process of spermatogenesis take
64days in biomedical physiology notes. 64-72 days - tissue biology
37
what does a spermatogonium turn into
a primary spermatocyte
38
what does a primary spermatocyte turn into
secondary spermatocyte
39
what does a secondary spermatocyte turn into
a spermatid
40
what does a spermatid turn into
a mature spermatazoa after undergoing packaging
41
where in spermatogenesis does meiosis 1 take place
when the primary spermatocyte divides into the secondary spermatocyte
42
where in spermatogenesis does meiosis 2 take place
when the secondary spermatocyte divides into the spermatids
43
what does kisspeptin signalling directly allow the secreition of from the hypothalamus
GnRH
44
in which part of the hypothalamus do the kiss1 neurones exist
in the arcuate nucleus of the hypothalamus
45
what do the kiss1 neurones release
kisspeptin
46
what does gnrh regulate
the release of lh and fsh from the anterior pituitary gland
47
list three functions of kisspeptin signalling
regulation of GnRH, initiating puberty and normal reproductive function
48
the sertoli cell is able to secrete inhibin to selectively inhibit the secretion of what fro the anterior pituitary gland
fsh secretion
49
the leydig cells can secrete testosterone to selectively inhibit what secretion from the anterior pituitary gland
lh secretion
50
the testosterone produced by the leydig cells can selectively inhibit lh secretion from the anterior pituitary gland. what else can it inhibit
the leydig cells producing the testosterone can result in the kiss 1 neurons producing less kisspeptin, producing less gnrh, producing less lh and fsh
51
oogenesis is for the production of
ova
52
list the four functions of oestrogen
ova maturation and release, development of female sex characteristics, transport of sperm, breast development
53
list two functions of progesterone
prepares environment to nourish developing embryo/foetus, breast gains the ability to produce milk
54
in the ovarian cycle, how long does the menstrual phase last
1-5 days
55
what happens during the proliferative phase
the lining builds
56
when does ovulation take place, which day
day 14
57
when does the secretory phase occur, which days
days 15-28
58
what happens in the follicular phase
maturing follicles are present , y
59
what happens in the luteal phase
the presence of the corpus luteum
60
what days is the follicular phase taking place
day 0-14
61
what days is the luteal phase taking place
14-28
62
what is taking place in the follicular phase
oogenesis
63
what secretion is taking place in the follicular phase
oestrogen
64
which three hormones are controlling the follicular phase of the cycle
fsh, lh and oestrogen
65
what happens in ovulation
the maturing follicle releases the ovum
66
what triggers the maturing follice to release the ovum during ovulation on day 14
triggered by a surge in LH
67
what hormone is in high levels in the ovulation phase
oestrogen
68
in the luteal phase what does the lh convert into what
lh converts empty follicle into the corpus leteum
69
which two hormones does the corpus luteum produce
oestrogen and progesteron
70
describe what happens if the ovum is fertilised
the corpus luteum prepares the uterus for implantation
71
explain what happens if the ovum is not fertilised
the corpus luteum degenerates, no hormonal support for the uterine lining so the endometrium disintegrates resulting in menstruation
72
where are lh and fsh secreted from
the anterior pituitary gland
73
where is oestrogen secreted from
from the follicle first and then from the corpus luteum
74
where is progesterone secreted from
from the corpus luteum
75
when does the placenta develop
post implantation
76
what is the placenta and what is it composed of
endocrine organ of pregnancy, maternal and foetal tissue
77
what are the two functions of the placenta
exchange of maternal and foetal blood, the secretion of hormones
78
list the three main hormones secreted by the placenta
HCG, oestrogen, progesterone
79
what does HCG stand for
human chorionic gonadotropin
80
list the two functions of HCG
1. maintains cl of pregnancy | 2. stimulates secretion of testosterone - developing testes in xy embryos
81
list two functions of oestrogen produced by the placenta
stimulates growth of myometrium, promotes development of ducts in mammary glands for lactation
82
progesterone supresses
uterine contractions to prevent miscarriage
83
progesterone promotes the formation of a
cervical mucus plug
84
progesterone stimulates the development of what to aid in lactation
milk glands for lactation
85
progesterone prevents ovulation by the inhibition of which hormones
inhibits GnRH, lh and fsh - prevents LH surge, stops ovulation occurring again
86
other than progesterone, oestrogen and hcg, list three other placental hormones
human chorionic somatomammotropin, relaxin and placental PTHrp
87
what is the function of the placental hormone human chorionic somatomammotropin
Its structure and function are similar to those of human growth hormone. It modifies the metabolic state of the mother during pregnancy to facilitate the energy supply of the fetus.
88
what is the function of the placental hormone relaxin
Relaxin is a hormone produced by the ovary and the placenta with important effects in the female reproductive system and during pregnancy. In preparation for childbirth, it relaxes the ligaments in the pelvis and softens and widens the cervix
89
what is the function of the placental hormone PTHrp
PTHrP is an important regulator of fetal blood calcium , for bones basicallyyyy
90
what does PTHrp stand for
Parathyroid hormone-related peptide
91
focusing in on the hormonal changes during pregnancy, what does the placenta secrete in the first trimester
secretes HCG
92
what does the corpus luteum secrete during the first trimester of pregnancy
oestrogen and progesterone
93
what does the placenta secrete in the second and third trimester of pregnancy
oestrogen, progesterone
94
where is the oestrogen from the third trimester of pregnancy synthesised
from the DHEA in the foetus
95
which hormone softens the cervix and loosens connective tissue
relaxin
96
which hormone stimulates the growth of the myometrium
oestrogen
97
which hormone maintains the cl of pregnancy
hcg
98
which hormone supresses uterine contractions
progesterone
99
which hormone stimulates the secretion of teststeone
hcg
100
the exact trigger for the initiation of paturation is unknown so there are four theories, what are they
1. high levels of oestrogen, 2. oxytocin 3. CRH from placenta 4. inflammation
101
high levels of oestrogen is a theory of parturition, what three things occur when there are high levels of oestrogen
1. promote synthesis of connexons 2. more myometrial receptors for ozytocin 3. promote production of local prostaglandins
102
one theory involves myometrial responsiveness reaching critical threshold to which hormone
oxytocin
103
what actually happens when the myometrial responsiveness to oxytocin reaches a critical threshold
it permits the onset of strong, coordinated contractions for labor
104
what does crh stand for
corticotropin releasing hormone
105
where is the corticotropin releasing hormone released from in parturition
secreted from the fetal portion of the placenta into both the maternal and fetal circulations
106
where is crh normally secreted from
Recall that CRH is normally secreted by the hypothala- mus and regulates the output of ACTH by the anterior pituitary. In turn, ACTH stimulates production of both cortisol and DHEA by the adrenal cortex.
107
what is the function of crh is parturition
regulates timing of parturition and promotes lung maturation
108
once theory initiation parturition is inflammation, what must be activated for the inflammatory response to proceed and induce labor
Key to this inflammatory response is activation of nuclear factor 􏰐B (NF-􏰐B) in the uterus.
109
what does nuclear factor b result in the release of
inflammatory cytokines and prostaglandins
110
give an example of positive feedback
parturition
111
describe how positive feedback occurs in parturition
increased uterine contractions, increased pressure on uterus wall by fetus, messages sent to brain (neuroendocrine reflex) to increase oxytocin secretion, oxytocin increases prostaglandin production and oxytocin itself increases uterine contrations,