Thermoregulation Flashcards
Brown fat
Non-shivering thermogenesis
Increases with GA
Found in axillary, mediastinal, paraspinal, perinephric, and interscapular areas
Non-shivering thermogenesis
Decrease in temperature -> Increased sympathetic activity-> Increased norepi and TSH-> T4 conversion to T3-> Thermogenin (Uncoupling protein 1)-> Uncouples mitochondrial phosphorylation in brown fat-> Fat oxidation and heat production
Neutral thermal environment
Energy consumption required to maintain normal body temp
Very narrow in preterm infants
Evaporation
Transfer of water from skin to the environment surrounding infant
Humidity helps prevent this
Conduction
Transfer of heat between contacting solid objects of different temperatures
Mattresses in incubators have very low conducivity
Convection
Heat exchange between a solid object and liquid or gas in the environment
Heated and humidified respiratory support is important
Radiation
Transfer of heat from a warm to a cooler surface
Double walled incubators decrease radiance by preventing loss of heat from baby to the walls of the room around them
Reducing heat loss in the delivery room
Increase environmental temp to at least 23-24 Celsius
Use of heated/humidified gas sources
Using exothermic mattress and plastic wrap
Placing infant under a radiant warmer