Nephrology Flashcards
Type 1 RTA (distal)
Diminished acid secretion in distal tubule
Urine pH >6.5
Potassium low normal
Hypercalciuria present
Type 2 RTA (proximal)
Diminished bicarb resorption
Urine pH <6.5
Potassium low normal
No hypercalciuria
Type 4 RTA
Aldosterone deficiency or resistance
Urine pH <6.5
Potassium high
No hypercalciuria
What happens if ureteric bud does not form
Renal agenesis
Pronephros
Disappears by fourth week of gestation
Mesonephros
Forms ureteric bud, absorbed into urogential sinus (testosterone)
Metanephros
Definitive kidney appears at fifth week of gestation
Most common congenital condition on prenatal Ultrasound?
Hydronephrosis
Most common cause of congenital Hydronephrosis?
Transient followed by UPJ obstruction
Triad of renal vein thrombosis
Flank mass
Hematuria
Thrombocytopenia
Site of action of acetazolamide
Proximal tubule
Site of action of loop diuretics
Thick ascending limb of loop of Henle
Site of action of thiazide diuretics
Distal convoluted tubule
Site of action of spironolactone
Distal tubule
Which RTA has nephrocalcinosis?
Type one (stONEs in type ONE)