Therapy studies Flashcards
What is the idea behind randomization?
Create comparable groups
What is concealed allocation?
Keeping the group assignment unknown to the clinical group
What is the intention to treat idea?
Subjects are analyzed in the group to which they were assigned
If less than what percent of a treatment group completed follow up, is the study invalid
80%
True or false: according to the intention to treat idea, all data from a group of people should be analyzed, even if some of them withdraw before the study was complete?
True
True or false: according to the intention to treat idea, all data from a group of people should be analyzed, even if some of them failed to take the assigned treatment?
True
True or false: according to the intention to treat idea, all data from a group of people should be analyzed, even if the were assigned to a different control group?
True
When the CI crosses what number, is the result of interest not statistically significant
1
EER is what?
Events in the experimental group
CER is what?
Events in the control group
What is the ARR?
CER-EER
What is the RRR (relative risk reduction)?
(CER-EER)/CER
NNT = ? (number needed to treat)
1/ARR
What, in words, is the number needed to treat?
Number of pts you would need to treat in order to achieve one “good” result
The lower the NNT, the (more or less) useful the intervention?
More useful
