Therapeutics Flashcards
1
Q
Which drugs are P450 enzyme inducers
A
Carbamazepine Rifampicin bArbiturates Phenytoin St John's Wort
2
Q
Which drugs are P450 enzyme inhibitors
A
Some certain silly compounds annoyingly inhibit enzymes, grrr
Sodium valproate ciprofloxacin sulphonamide Cimetidine/omeprozole Antifungals, amiodarone Isoniazid Erythromycin/clarithromycin Grapefruit juice
3
Q
Which drugs are affected by P450 metabolism
A
warfarin COCP theophylline corticosteroids tricyclics pethidine statins
4
Q
Name some drugs with narrow therapeutic ranges
A
lithium digoxin gentamicin warfarin methotrexate theophylline phenytoin insulin ciclosporin