Therapeutic Drug Monitoring/Toxicity Flashcards

1
Q

List the active metabolites of procainamide, primidone, and theophylline.

A

Procainamide: n-acetyl procainamide
Primidone: phenobarbital
Theophylline: caffeine

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2
Q

Digoxin

A

Cardioactive

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3
Q

Lidocaine

A

Cardioactive

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4
Q

Procainamide

A

Cardioactive

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5
Q

Phenobarbital

A

Anticonvulsant

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6
Q

Phenytoin

A

Anticonvulsant

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7
Q

Primidone

A

Anticonvulsant

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8
Q

Carbamazepine

A

Anticonvulsant

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9
Q

Valproic acid

A

Anticonvulsant

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10
Q

Caffeine

A

Bronchodilator

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11
Q

Theophylline

A

Bronchodilator

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12
Q

Aminoglycosides (Gentamicin, Tobramycin, Amikacin, Neomycin, Streptomycin)

A

Antibiotic (Antimicrobial)

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13
Q

Chloramphenicol

A

Antibiotic (Antimicrobial)

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14
Q

Vancomycin

A

Antibiotic (Antimicrobial)

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15
Q

Lithium

A

Anti-Psychotic

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16
Q

Serotonin-selective reuptake inhibitors (SSRIs)

A

Anti-Psychotic

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17
Q

Serotonin-release inhibitors (SRI’s)

A

Anti-Psychotic

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18
Q

Tricyclic antidepressants

A

Anti-Psychotic

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19
Q

Alkylating agents

A

Antineoplastic

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20
Q

Methotrexate

A

Antineoplastic

21
Q

Cyclosporine

A

Immunosuppressant

22
Q

Mycophenolic acid (MPA)

A

Immunosuppressant

23
Q

Sirolimus (Rapmycin)

A

Immunosuppressant

24
Q

Tacrolimus (Prograf or FK-506)

A

Immunosuppressant

25
Q

List the toxic metabolite(s) of ethanol

A

Acetaldehyde

26
Q

List the toxic metabolite(s) of methanol

A

Formaldehyde and formic acid

27
Q

List the toxic metabolite(s) of isopropanol

A

Acetone

28
Q

List the toxic metabolite(s) of ethylene glycol

A

Glycolic, oxalic, formic acid

29
Q

Benzodiazepines

A

Depressants

30
Q

Short- and long-acting barbiturates

A

Depressants

31
Q

Amphetamine

A

Stimulates

32
Q

Methamphetamine

A

Stimulates

33
Q

MDMA (“Ecstasy”)

A

Stimulates

34
Q

Cocaine

A

Stimulates

35
Q

Opiates/Opioids
 Codeine
 Morphine
 Heroin
Opioids
 Hydrocodone
 Oxycodone
 Hydromorphone
 Oxymorphone
 Fentanyl

A

Narcotics

36
Q

Methadone

A

Narcotics

37
Q

Buprenorphine

A

Narcotics

38
Q

Cannabinoids (THC)

A

Hallucinogens

39
Q

Phencyclidine (PCP)

A

Hallucinogens

40
Q

Lysergic acid diethylamide (LSD)

A

Hallucinogens

41
Q

Acetaminophen

A

Analgesics (may be abused)

42
Q

Acetylsalicylic acid

A

Analgesics (may be abused)

43
Q

Amitriptyline

A

Tricyclic Antidepressants

44
Q

Desipramine

A

Tricyclic Antidepressants

45
Q

Nortriptyline

A

Tricyclic Antidepressants

46
Q

Imipramine

A

Tricyclic Antidepressants

47
Q

Phenothiazines

A

Other drugs of abuse

48
Q

Ketamine

A

Other drugs of abuse

49
Q

Cotinine

A

Other drugs of abuse