Therapeutic Drug Monitoring/Toxicity

Question 1

List the active metabolites of procainamide, primidone, and theophylline.

Answer 1

Procainamide: n-acetyl procainamide
Primidone: phenobarbital
Theophylline: caffeine

Question 2

Digoxin

Answer 2

Cardioactive

Question 3

Lidocaine

Answer 3

Cardioactive

Question 4

Procainamide

Answer 4

Cardioactive

Question 5

Phenobarbital

Answer 5

Anticonvulsant

Question 6

Phenytoin

Answer 6

Anticonvulsant

Question 7

Primidone

Answer 7

Anticonvulsant

Question 8

Carbamazepine

Answer 8

Anticonvulsant

Question 9

Valproic acid

Answer 9

Anticonvulsant

Question 10

Caffeine

Answer 10

Bronchodilator

Question 11

Theophylline

Answer 11

Bronchodilator

Question 12

Aminoglycosides (Gentamicin, Tobramycin, Amikacin, Neomycin, Streptomycin)

Answer 12

Antibiotic (Antimicrobial)

Question 13

Chloramphenicol

Answer 13

Antibiotic (Antimicrobial)

Question 14

Vancomycin

Answer 14

Antibiotic (Antimicrobial)

Question 15

Lithium

Answer 15

Anti-Psychotic

Question 16

Serotonin-selective reuptake inhibitors (SSRIs)

Answer 16

Anti-Psychotic

Question 17

Serotonin-release inhibitors (SRI’s)

Answer 17

Anti-Psychotic

Question 18

Tricyclic antidepressants

Answer 18

Anti-Psychotic

Question 19

Alkylating agents

Answer 19

Antineoplastic

Question 20

Methotrexate

Answer 20

Antineoplastic

Question 21

Cyclosporine

Answer 21

Immunosuppressant

Question 22

Mycophenolic acid (MPA)

Answer 22

Immunosuppressant

Question 23

Sirolimus (Rapmycin)

Answer 23

Immunosuppressant

Question 24

Tacrolimus (Prograf or FK-506)

Answer 24

Immunosuppressant

Question 25

List the toxic metabolite(s) of ethanol

Answer 25

Acetaldehyde

Question 26

List the toxic metabolite(s) of methanol

Answer 26

Formaldehyde and formic acid

Question 27

List the toxic metabolite(s) of isopropanol

Answer 27

Acetone

Question 28

List the toxic metabolite(s) of ethylene glycol

Answer 28

Glycolic, oxalic, formic acid

Question 29

Benzodiazepines

Answer 29

Depressants

Question 30

Short- and long-acting barbiturates

Answer 30

Depressants

Question 31

Amphetamine

Answer 31

Stimulates

Question 32

Methamphetamine

Answer 32

Stimulates

Question 33

MDMA (“Ecstasy”)

Answer 33

Stimulates

Question 34

Cocaine

Answer 34

Stimulates

Question 35

Opiates/Opioids  Codeine  Morphine  Heroin Opioids  Hydrocodone  Oxycodone  Hydromorphone  Oxymorphone  Fentanyl

Answer 35

Narcotics

Question 36

Methadone

Answer 36

Narcotics

Question 37

Buprenorphine

Answer 37

Narcotics

Question 38

Cannabinoids (THC)

Answer 38

Hallucinogens

Question 39

Phencyclidine (PCP)

Answer 39

Hallucinogens

Question 40

Lysergic acid diethylamide (LSD)

Answer 40

Hallucinogens

Question 41

Acetaminophen

Answer 41

Analgesics (may be abused)

Question 42

Acetylsalicylic acid

Answer 42

Analgesics (may be abused)

Question 43

Amitriptyline

Answer 43

Tricyclic Antidepressants

Question 44

Desipramine

Answer 44

Tricyclic Antidepressants

Question 45

Nortriptyline

Answer 45

Tricyclic Antidepressants

Question 46

Imipramine

Answer 46

Tricyclic Antidepressants

Question 47

Phenothiazines

Answer 47

Other drugs of abuse

Question 48

Ketamine

Answer 48

Other drugs of abuse

Question 49

Cotinine

Answer 49

Other drugs of abuse