Therapeutic Drug Monitoring/Toxicity Flashcards

1
Q

List the active metabolites of procainamide, primidone, and theophylline.

A

Procainamide: n-acetyl procainamide
Primidone: phenobarbital
Theophylline: caffeine

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2
Q

Digoxin

A

Cardioactive

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3
Q

Lidocaine

A

Cardioactive

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4
Q

Procainamide

A

Cardioactive

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5
Q

Phenobarbital

A

Anticonvulsant

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6
Q

Phenytoin

A

Anticonvulsant

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7
Q

Primidone

A

Anticonvulsant

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8
Q

Carbamazepine

A

Anticonvulsant

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9
Q

Valproic acid

A

Anticonvulsant

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10
Q

Caffeine

A

Bronchodilator

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11
Q

Theophylline

A

Bronchodilator

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12
Q

Aminoglycosides (Gentamicin, Tobramycin, Amikacin, Neomycin, Streptomycin)

A

Antibiotic (Antimicrobial)

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13
Q

Chloramphenicol

A

Antibiotic (Antimicrobial)

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14
Q

Vancomycin

A

Antibiotic (Antimicrobial)

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15
Q

Lithium

A

Anti-Psychotic

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16
Q

Serotonin-selective reuptake inhibitors (SSRIs)

A

Anti-Psychotic

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17
Q

Serotonin-release inhibitors (SRI’s)

A

Anti-Psychotic

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18
Q

Tricyclic antidepressants

A

Anti-Psychotic

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19
Q

Alkylating agents

A

Antineoplastic

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20
Q

Methotrexate

A

Antineoplastic

21
Q

Cyclosporine

A

Immunosuppressant

22
Q

Mycophenolic acid (MPA)

A

Immunosuppressant

23
Q

Sirolimus (Rapmycin)

A

Immunosuppressant

24
Q

Tacrolimus (Prograf or FK-506)

A

Immunosuppressant

25
List the toxic metabolite(s) of ethanol
Acetaldehyde
26
List the toxic metabolite(s) of methanol
Formaldehyde and formic acid
27
List the toxic metabolite(s) of isopropanol
Acetone
28
List the toxic metabolite(s) of ethylene glycol
Glycolic, oxalic, formic acid
29
Benzodiazepines
Depressants
30
Short- and long-acting barbiturates
Depressants
31
Amphetamine
Stimulates
32
Methamphetamine
Stimulates
33
MDMA (“Ecstasy”)
Stimulates
34
Cocaine
Stimulates
35
Opiates/Opioids  Codeine  Morphine  Heroin Opioids  Hydrocodone  Oxycodone  Hydromorphone  Oxymorphone  Fentanyl
Narcotics
36
Methadone
Narcotics
37
Buprenorphine
Narcotics
38
Cannabinoids (THC)
Hallucinogens
39
Phencyclidine (PCP)
Hallucinogens
40
Lysergic acid diethylamide (LSD)
Hallucinogens
41
Acetaminophen
Analgesics (may be abused)
42
Acetylsalicylic acid
Analgesics (may be abused)
43
Amitriptyline
Tricyclic Antidepressants
44
Desipramine
Tricyclic Antidepressants
45
Nortriptyline
Tricyclic Antidepressants
46
Imipramine
Tricyclic Antidepressants
47
Phenothiazines
Other drugs of abuse
48
Ketamine
Other drugs of abuse
49
Cotinine
Other drugs of abuse