The telomere effect Flashcards
Telomeres are specific DNA protein structures at the end of _________. They play a vital role in __________ information for genome
Chromosomes
preserving
Senescence or _______________ occurs when the telomere reaches a short length. It serves as a biological clock
Apoptosis
TL is maintained by the enzyme ____________
telomerase
We can’t prevent aging through telomerase supplementation because it can result in ____________ development
cancer
genes load the gun, environment ___________
pulls the trigger
First cellular enemy is ___________.Results in telomere shortening (processed foods, refined carbs, sodas, cytokine production)
inflammation
Alcohol consumption increases CRP (increases with inflammation). When inflammation is low, telomere dysfunction
decreases
Second enemy: __________________. Too many free radicals and not enough antioxidants can damage DNA sequence and shorten telomeres, decrease the enzyme ___________
oxidative stress
telomerase
Free radical remedies include _____________ nutrients such as Vit C, E and A. Supplement but also lower levels of F2 isoprostane which is a marker of ___________
antioxidants
oxidative stress
Third enemy: _________ resistance, results in 5 extra years of biological aging.
insulin
Foods associated with shorter telomeres vs longer
red meat, white bread, saturated fat, alcohol
fruits, vegetables, whole grains
Cellular aging begins in the _________ as telomeres are beginning to be shaped
womb
Mothers diet can influence baby’s telomere length as parents telomeres can be ___________ to developing fetus
passed
Essential pregnancy nutrition points include protein, ______ (natural antioxidant found in mitochondria), folate and protective nutrients such as vitamin ___ and ___, probiotics
Co-enzyme, b and D
