The Oral Environment 3 Flashcards

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1
Q

What is the volume of saliva in the mouth?

A

1.1 ml (range = 0.5ml-2.1ml)

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2
Q

What is the area in the mouth that saliva is dispersed over?

A

Approximately 200cm2

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3
Q

What is the thickness of the film of saliva that covers the mucosa?

A

50-100 nanometres

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4
Q

Is the film of saliva in the mouth in motion or static?

A

In motion

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5
Q

Where is salivary flow highest in the mouth?

A

In lower, lingual regions

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6
Q

Where is salivary flow lowest in the mouth?

A

In labial and buccal regions

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7
Q

What is meant by clearance?

A

Refers to the rate at which substances are removed from the mouth

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8
Q

What factors is clearance related to?

A
  • Salivary film velocity

- Location in mouth

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9
Q

What are the important oral health aspects of clearance?

A
  • Removal of ‘harmful’ materials

- Retention of ‘beneficial’ materials

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10
Q

What is rapid clearance?

A

High salivary flow rates

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11
Q

What is slow clearance?

A

Low salivary flow rates

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12
Q

How do plaque micro-organisms generate acid?

A

By metabolising sugars such as sucrose

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13
Q

What is a graph of the plaque pH change over time called?

A

A Stephen curve

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14
Q

What are examples of bulk caloric (cariogenic) sweeteners?

A
  • Sucrose
  • Fructose
  • Glucose
  • Lactose
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15
Q

What are non-caloric/high intensity sweeteners (non-cariogenic)?

A
  • Aspartame
  • Cyclamates
  • Saccharin
  • Sucralose
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16
Q

What are low caloric sweeteners?

A
  • Mannitol
  • Sorbitol
  • Xylitol
17
Q

When do patients complain of ‘dry mouth’?

A

When salivary flow rates fall below 50% of normal levels

18
Q

What is the unstimulated flow rate of a person with Xerostomia?

A

< 0.1ml/min

normal = 0.2-0.4 ml/min

19
Q

What is the stimulated flow rate of a person with Xerostomia?

A

< 0.5ml/min

normal = 1.0-5.0 ml/min

20
Q

What are the causes of decreased salivary flow?

A
  • Side effect of many drugs
  • Radiotherapy
  • Diseases:
  • Specific salivary gland diseases
  • Systemic diseases that also affect salivary glands
  • More general conditions that may affect salivary glands
21
Q

What is a condition that affects salivary glands and other tissues?

A

Sjogren’s syndrome

22
Q

What type of carried can be related to reduced salivary flow and clearance?

A

Cervical caries

23
Q

What are the consequences of decreased salivary flow?

A
  • Increased dental caries
  • Increased oral disease
  • Dysaesthesia (‘burning’ mouth)
  • Impaired oral function
  • Diminished taste perception
24
Q

What are the protective components that are lost with decreased salivary flow?

A
  • Antimicrobial agents
  • Buffering
  • Decreased remineralisation
  • Mucins and other proteins
  • Gustin
  • Consumption of cariogenic confectionary to increase salivation
25
Q

How can you treat Xerostomia?

A
  • If there is functioning gland tissue present, stimulate salivary flow for example by chewing or by drugs
  • If there is no functioning gland tissue, saliva substitutes may be used:
  • Mucin-based; cellulose based
  • Water along is not very effective