The nervous system Flashcards

1
Q

Glial cells- general function

A
  • surround the axon and dendrites of neurons

- provide physical and metabolic support

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2
Q

astrocyte function

A
  • regulate composition of the extracellular fluid in the CNS by removing K+ and neurotransmitters around synapses
  • stimulate formation of tight junctions between cells that make up the walls around capillaries
  • sustain neurons metabolically (provide nutrients and remove waste
  • secrete growth factors
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3
Q

ogliodendrocyte

A

form mylein sheath in the CNS

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4
Q

shwann cells

A

form mylein sheath in the PNS

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5
Q

microglia

A

microphage like cells that peform immune function in the CNS

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6
Q

Mylein

A

-concentric lipid rich layers

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7
Q

direction of calcium, cloride, sodium and pottasium

A

in, in, in, out

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8
Q

glutamate

A

excitatory neurotransmitter important for learning and memory

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9
Q

somatic stimuli

A
  • muscle length and tension

- propioception

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10
Q

visceral stimuli

A

Blood pressure, ph of blood and spinal fluid, oxygen content of blood, lung inflation, osmolarity of body fluids, temperature, glucose levels of blood

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11
Q

somatic senses

A

touch, temperature, pain, itch, propioception

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12
Q

special senses

A

vision, hearing, taste, smell, equilibrium

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13
Q

temporal summation

A

two potentials arriving in a short space of time, rate is increased

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14
Q

spatial summation

A

many ion channels are opened at once

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15
Q

Graded Potential

A
  • changes in membrane potential (hyperpolarising or depolarising) that are confined to a relatively small area of the plasma membrane
  • magnitude can vary and is related to initiation event
  • function as signals only over short distances (unless summation occurs)
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16
Q

NMDA receptor

A
  • opens in response to glutamate, allowing Na and Ca influx
17
Q

Snare proteins

A

initiate movement of vesicles to the membrane during exocytosis of neurotransmitters

18
Q

PNS: somatic

A
  • control of skeletal muscle via motor neurones
19
Q

PNS: Sensory

A
  • relays information to the CNS about the internal and external environment via afferent pathways
20
Q

PNS: autonomic

A
  • regulates smooth muscle and gland function
21
Q

somatic excitation pathway

A
  • consists of one cholinergic neurone; no synapses or ganglia
  • synapses at a skeletal muscle neuromuscular junction consisting of axon terminals and motor end plates (region of skeletal muscle fibre containing many receptors)
  • receptors are always nicotinic choliergic
22
Q

ACh nicotinic receptor action

A

non selective iontropic opening, net excitation

23
Q

slowly adapting receptors

A

neurones which persistently fire action potentials throughout period of stimulation

24
Q

Rapidly adapting receptors

A

only respond when conditions are altered

25
Q

Sympathetic pathway

A
  • short preganglionic neurone: releases ACh which binds to nicotinic receptors
  • long post ganglionic: releases noradrenaline binds to g protein coupled receptor
26
Q

parasympathetic pathway

A

long pre-ganglionic neurone: releases ACh which binds to a nicotinic receptor
Short post-ganglionic neurone: Releases ACH that binds to muscarinic receptors on the post-synaptic membrane

27
Q

Simple receptor

A

neurones with free nerve endings

28
Q

complex receptor

A

nerve enclosed in connective tissue capsule

29
Q

Complex non neural cells

A

cells that release neurotransmitters onto sensory neurones, initiating an action potential