Action potential Flashcards
1
steady resting membrane potential is near Ek, due to leaky K+ channels
2
action potential begins with a depolarising stimulus, bringing the membrane potential to the threshold level (aprox -60). Depolarisation becomes a positive feedback loop, opening more Na+ channels
3-overshoots
Membrane potential overshoots, Ek approaches Pna
4-reaches peak
Na+ permeability rapidly declines as channels are blocked (inactivation) delayed opening of K+ halts membrane depolarisation
5- repolarisation
outward current through K+ channels brings membrane potential closer to original, negative potential.
6-hyperpolarised
current through slowly closing K+ channels hyperpolarises membrane.
7
closure of K+ channels returns membrane to resting potential.