the nervous system Flashcards
Explain why there is a difference in colour between grey and white matter (1)
grey matter contains cell bodies
What is the name given to the cells which partially cover neurones (1)
shwaan cell
What is the name given to the material which the cells produce to cover the axon (1)
myelin
What is the function of this material in the conduction of an action potential (2)
- insulates the axon
- allows saltatory conduction/ impulse jumps from node to nod
- so speeding up the transmission of the action potential/ increase speed of conduction
Multiple scleropsis is a progressive, degenerative disease of the nervous system in which myelin sheath is destroyed. Symptoms include increasing muscle weakness and loss of vision suggest an explanation for these symptoms (2)
- impulses cannot jump from node to node/ saltatory conduction is stopped/ local circuits are too short/ voltage gate Na+ channels between nodes of ranvier
- so action potential cannot be generated/ speed of conduction is reduced/ action potential does not reach destination
Suggest a possible medical treatment for multiple sclerosis (1)
- remyelinate the axon
- use of stem cells
- make the membrane add Na+ channels in bare areas
- prevet further ddemyelination
- immune suppressants/inhibitory frugs
Give two ways in which the nerve net differes from the nervous system of a vertebrate (2)
- responds to limited number of stimuli
- cannot detect source of stimulus/ impulse passes in all directions
- number of effectors is mall
- no CNS
- action potential can be carried in more than one direction along a neurone
- one type of cell/ unmyelinatied / slower response
Describe how the resting potential is maintained in the neurone (3)
- sodium potassium pump
- ATP/active transport
- 3Na+ out and 2K+ in
- organic anions negative charged molecules/ proteins
- -70mv potential difference across membrane
- membrane leakage more permeable to K+ than Na+
What is taking place at -70mv
an at +40mv (5)
-70mv
* threshold reached
* sodium voltage gated channels open
* sodiums ion diffuse into cytoplam
* depolarised
+40mv
* sodium voltage gated channels close
* potassium voltage gated channels open
* potassium diffuses out
* sodium/ potassium pumps
* repolarised
Multiple sclerosiss is caused by the immune system destroying th myelin sheath of nerones. Explain why this condiytion leads to the slowing down of the transmission of a nerve impulse (3)
- myelin sheath electrical insulation
- ions exchange only at nodes of ranvier/ depolarisation only at nodes
- action potential jumps from one node of ranvier to next
- saltatory conduction
- if no myelin sheath local circuits
- altatory conduction must faster than local circuits
Suggest the ways in which chemicals could increase activity of the nervous system (2)
- mimic action of normal transmitters/ bind to receptors
- prevents breakdown of transmitter
- stimulate release of transmitters
- reduce threshold for excitation of posst synaptic membranes
Suggest ways that chemical can decrease actviity in the nervous system (2)
- block receptors on posty synaptic membrane
- prevent Ca2+ being released
- prevent exocytosis
- prevents recycling of neurotransmitter /active tranport back across presynaptic membrane
- raises threshold
- changes shape of neurotransmitter
Name the cell that forms myelin sheath (10
schwaan cell
Explain in terms of movement of ions what causes the rise of membrane potential from -70mv to 40mv (2)
- voltage gated sodium channels open/ increase in sodium ion permeability
- sodium ions diffuse/flood/rush/sudden influx in
state the name given to the name to the rapid fall in membrane potential (1)
repolarisation
Suggest how cardiac muscle fibres would respond when the voltage across the membrane rises (1)
contraction
The cardiac muscle fibres used to obtain the oscilloscope trace where obtained from a frogs heart. Consider the ethics of killing a frog to obtain cardica muscle fibre one argument in favour and one against (2)
- frog has a right to life / suffering/ pain/distres/ harm of frogs/ frogs are scarce in the wild
- benefits to medicine/ health of the heart
What units is membrane potential (1)
mv