The Nervous System Flashcards
The nervous system divides into:
The peripheral and central nervous system
The central nervous system consists of:
the brain and the spinal cord
The peripheral nervous system consists of
- Somatic Nervous System
- Autonomic Nervous System
The autonomic nervous system consists of
- Sympathetic nervous system
- Parasympathetic nervous system
3 main parts of the brain
- Cerebrum
- Cerebellum
- Brain stem
Subparts of the cerebrum (2)
- Telencephalon
- Diencephalon
Subparts of the brain stem (3)
- Mid brain
- Pons
- Medulla oblongata
The brain boasts three poles:
- Frontal pole
- Temporal pole
- Occipital pole
Telencephalon
- largest and most recently evolved area of the brain
- shaped like a boxing glove
- divided into left and right hemisphere by sagittal fissure
Horizontal fissure
- separates the telencephalon from the cerebellum
- has a lateral fissure which separates the temporal lobe from the upper part of the cerebrum
Frontal lobe
Parietal lobe
Occipital lobe
Occipital lobe
Temporal lobe
The cortex
- the outer covering of the hemisphere
- has many folds
Pre-central sulcus
Central sulcus
Post-central sulcus
Pre-central gyrus
Post-centrl gyrus
Lateral sulcus
Components of the diencephalon (4)
- thalamus
- hypothalamus
- subthalamus
- epithalamus
Thalamus
a large nucleus located on both sides of the third ventricle; it is the main sensory nucleus of the brain handling every sense apart from smell
Hypothalamus
situated below the thalamus and connected directly to the pituitary gland, which hangs from it
Subthalamus
a small nucleus located below the thalamus
Epithalamus
another small nucleus located below the thalamus
Cerebrum
Midbrain
Diencephalon
Pons
Medulla
Spinal cord
Cerebellum
Lateral ventricles
Caudate nucleus of the basal ganglia
Lentiform nucleus of the basal ganglia
3rd ventricle
Internal capsule
Thalamus
Corpus callosum
Grey matter of the cerebrum contains:
the cell bodies of the neurons (nerve cells)
Basal ganglia (3)
- Lentiform nucleus
- Caudate nucleus
- Amygdala
Spinal cord
Medulla
Pons
Midbrain
3rd ventricle
Corpus callosum
Parieto-occipital sulcus
Calcarine sulcus
4th ventricle
3 types of fibers of white matter
- Association fibers
- Commissural fibers
- Projection fibers
Association fibers
are for communication within one hemisphere and can be long, short, or intermediate
Commissural fibers
are for communication between the hemispheres
3 sets of commisural fibers in the brain
- the small anterior commissure
- the tiny posterior commissure
- the huge corpus callosum
Projection fibers
- communicate between different levels of the nervous system
- pass from one level of the nervous system to another
Describe the pathway fibers of the Pyramidal tract take
fibers pass from the motor cortex, down through the internal capsule, through the cerebral peduncles, through the pons and medulla to the spinal cord and eventually to the spinal level of their target tissue
The midbrain has two large fiber bundles
- anteriorly the cerebral peduncles
- posteriorly the paired superior and inferior colliculi
Pons
bridges the cerebellar hemispheres
Medulla oblangata
- continuous with the spinal cord
- on the anterior sureface are the paired pyramids medially and the olives laterally
Cerebellum
- responsible for coordination
- its main connection to the brain stem is via the large middle cerebellar peduncles
Cerebellum
Inferior colliculus
Superior colliculus
Midbrain
Mammillary body
Oculomotor nerve
Pons
4th ventricle
Central canal
Medulla
Spinal cord
Cervical enlargement
Lumbar enlargement
Conus medullaris
Filum terminale
Cauda equina
The spinal cord extends in the ___________ from the __________ down to _____
- vertebral canal
- foramen magnum
- L 1/2
Ventral root
Spinal nerve
Dorsal root ganglion
Dorsal root
Posterior horn
Intermediate horn (T1-L2)
Anterior horn
Dorsal funiculus
Ventral funiculus
Lateral funiculus
The anterior horns are responsible for:
motor function
The posterior horns are responsible for:
sensory function
The ventricular system
The CNS contains a fluid-filled system of chambers known as ventricles and ducts
Lateral ventricles
- numerically: ventricles 1 and 2
- anterior horn (in the frontal lobe)
- posterior horn (in the occipital lobe)
- inferior horn (in the temporal lobe)
- body (in the parietal lobe)
Atrium of the ventricles
- the wide posterior part of the body joining the posterior and inferior horns
- contain choroid plexuses
- filled with cerebrospinal fluid (CSF)
- connect to the third ventricle via the paired foramina of monro
Third ventricle
- thin, sagittally oriented space located between the two halves of the thalamus
- joined to the fourth ventricle by the aqueduct of sylvius which passes through the midbrain
Fourth ventricle
- diamond-shaped space between the pons and medulla in front and the cerebellum behind
- is continuous with the central canal of the spinal cord
In the fourth ventricle, CSF travels from the ____________ and _________ into the _____________.
Foramina of luschka; foramen of magendie; subarachnoid space
Anterior horn
Body
Posterior horn
Inferior horn
3rd ventricle
Foramen of munro
Aqueduct
4th ventricle
Central canal
Foramen of Monro
Lateral ventricle
4th ventricle
Central canal
Foramina of Luschka
Aqueduct
3rd Ventricle
Meninges
specialized connective tissue that encases the CNS
From outermost to innermost, they three layers of meninges are:
- Dura mater
- Arachnoid mater
- Pia mater
Dura mater
- closest to surrounding bone
- invaginates into the sagittal fissure to form the falx cerebri
- invaginates into the horizontal fissure as the tentorium cerebelli
- contains channels: the dural venous sinuses
- covers the brain and extends down the vertebral canal as far as the sacrum
- has a fat-filled space between it and the vertrebral column called the epidural space
Arachnoid mater
- contains blood vessels
- invaginates into the fissures and extends a short way into the sulci
- attaches to the pia mater in the cranial vault, creating the subarachnoid space for CSF to circulate
- is firmly attached to the dura in the vertebral column
- is connected to the pia in the verterbal column by the denticulate ligaments
Pia matter
- attached to the superficial cortex and to the outer surface of the spinal cord
- is the outer layer of the CNS
Skull
Pia
Arachnoid
Dura
Pia
Denticulate ligaments
Arachnoid
Dura
Dura
Falx cerebri
Arachnoid
Pia
Tentorium cerebelli
Skull
Epidural space
Vertebrae
Denticulate ligaments
Dural & arachnoid
Lumbar cistern
Choroid plexuses
- produces cerebral spinal fluid in the ventricles from filtered arterial blood
CSF circulation
- It passes from the lateral ventricles, through the foramina of Monro to the third ventricle and through the aqueduct to the fourth ventricle and central canal.
- It passes into the subarachnoid space via the foramina of Luschka and Magendie.
- It then circulates all around the CNS in the subarachnoid space, providing a shock absorptive function.
- It eventually passes from the subarachnoid space in the region of the root of the falx. In this region, the arachnoid mater penetrates through the dura into the superior sagittal sinus.
- The CSF can thus filter through the arachnoid villi into the sinus, which is also filled with venous blood.
- The sinuses eventually empty into the internal jugular vein.
Superior sagittal sinus
Skull
Dura
Arachnoid
Subarachnoid space
Arachnoid villus
The brain recieves blood from two sources
- the internal carotid arteries
- the vertebral arteries
The internal carotid arteries reach inside the skull via the:
carotid canal
The vertebral arteries reach the inside of the skull via the:
foramen magnum
The vertebral arteries connect to form the;
basilar artery (runs up the pons)
The basilar artery divides in two to form the two:
Posterior cerebral arteries
Middle cerebral arteries
Posterior communication arteries
Posterior cerebal arteries
Basilar artery
Vertebral artery
Subclavian artery
Brachiocephalic artery
Common carotid artery
External carotid artery
Internal carotid artery
Anterior communicating artery
Anterior cerebral arteries
Anterior cerebral artery
Middle cerebral artery
Posterior cerebral artery
Right internal carotid arteries
Right common carotid artery
Right subclavian artery
Brachiocephalic artery
Aortic arch
Left subclavian artery
Left common carotid artery
Vertebral arteries
Left internal carotid arteries
Basilar artery
Posterior communicating artery
Anterior communicating artery
Functions of the somatic system
- provides voluntary motor control and general sensation information
- consists of 31 or 32 pairs of spinal nerves and twelve pairs of cranial nerves
Spinal nerves
exit the spinal cord and the vertebral column through the intervertebral foramina
Dorsal root
each nerve has a dorsal root which receives sensory information
Ventral root
each nerve has a ventral root which sends motor information
Dorsal ramus and ventral ramus
the spinal nerves exit their intervertrbral foramina and split into a small dorsal ramus and a large ventral ramus
Dorsal root ganglia
the cell bodies of the sensory nerves are found in the dorsal root ganglia
How are the spinal nerves classified?
alphanumerically according to their spinal levels
C1-C8
- cervical nerves
- exit above their corresponding vertebrae
T1-T12
- thoracic nerves
- exit below their corresponding vertebrae
L1-L5
- lumbar nerves
- exit below their corresponding vertebrae
S1-S5
- sacral nerves
-exit below their corresponding vertebrae
Autonomic system
provides involuntary motor control and visceral sensory perception
Major pathways of the somatic nervous system
- Sensory pathways (Ascending)
- Motor pathways (Descending)
Sensory modalities (6)
- touch - discriminatory (fine)
- touch - non-discriminatory (crude)
- pain
- temperature
- joint position - proprioception
- vibration
Important tracts in the sensory pathway
- dorsal columns
- anterolateral columns
Dorsal columns
- carry discriminatory touch, joint position and vibration
- fibers run from below T6 and travel in the fasciculus gracilis
- fibers above T6 travel in the fasciculus cuneatus
- the pathway ascends into the brain stem in the medial lemniscus and synapses again in the thalamus
- the pathway goes through the internal capsule and ends on the postcentral gyrus in the sensory cortex
Anterolateral columns
- carries crude touch, pain and temperature sensations
- the second axon of this system crosses over and ascends in the naterolateral tracts
Motor pathways
initiate movement in the muscles
Tracts of the Motor pathways
- Corticospinal tract
- Other motor tracts
Corticospinal tract
- most direct motor pathway
- motor activity is initiated in the motor cortex and the premotor activity
- fibers travel down through the internal capsule, the cerebral peduncles, the pons and then through the pyramids of the medulla
- in the lower medulla, fibers crossover and form the lateral corticospinal tract
- the rest of the fibers remain on the same side to form the anterior corticospinal tract
Fasciculus gracilis
Fasciculus cuneatus
Anterolateral tracts
Anterior corticospinal tract
Lateral corticospinal tract
Dorsal columns
T2
T8
L1
L3
S1
Dorsal columns
Nuclei gracilus and cuneatus
Fasciculus cuneatus
Fasciculus gracilus
Lumbar enlargement for lower limb
Cervical enlargement (for brachial plexus)
Anterolateral spinothalamic tract
Medial lemniscus
Antero and lateral funiculi
Internal capsule
Lentiform nucleus
Thalamus
Corticospinal tract
Pyramid of medulla
Lateral cortico-spinal tract
Anterior track
Ventral root
Anterior corticospinal tract
Decussation of the pyramids
CN #1 (Name, Type, Action, Foramen)
- Olfactory
- Sensory
- Smell
- Cribriform plate
CN #2 (Name, Type, Action, Foramen)
- Optic
- Sensory
- Sight
- Optic canal
CN #3 (Name, Type, Action, Foramen)
- Oculomotor
- Motor
- Eye movement
- Superior orbital fissure
CN #4 (Name, Type, Action, Foramen)
- Trochlear
- Motor
- Eye movement
- Superior orbital fissure
CN #5 (Name, Type, Action, Foramen (V1, V2, V3))
- Trigeminal
- Both
- Face sensation and muscles of mastication
- V1: Superior oribital fissure
- V2: Foramen rotundum
- V3: Foramen ovale
CN #6 (Name, Type, Action, Foramen)
- Abducens
- Motor
- Eye movement
- Superior orbital fissure
CN #7 (Name, Type, Action, Foramen)
- Facial
- Both
- Facial expression and taste
- Stylomastoid foramen
CN #8 (Name, Type, Action, Foramen)
- Vesibulococlear
- Sensory
- Hearing and balance
- Internal acoustic meatus
CN #9 (Name, Type, Action, Foramen)
- Glossopharyngeal
- Both
- Taste and general sensation
- Jugular foramen
CN #10 (Name, Type, Action, Foramen)
- Vagus
- Both
- Larynx sense and movement
- Jugular foramen
CN #11 (Name, Type, Action, Foramen)
- Spinal accessory
- Motor
- Upper limb movement
- Jugular foramen
CN #12 (Name, Type, Action, Foramen)
- Hypoglossal
- Motor
- Tongue movement
- Hypoglassal canal
Opthalmic Component (Name, Type, Action, Foramen)
- Trigeminal Nerve V1
- Sensory
- Forehead movement
- Enters via Superior orbital fissure
Maxillary Component (Name, Type, Action, Foramen)
- Trigeminal Nerve V2
- Sensory
- Cheek movement
- Enters via Foramen rotundum
Mandibular Component (Name, Type, Action, Foramen)
- Trigeminal Nerve V3
- Sensory and motor
- Jaw movement
- Enters/exits via Foramen ovale
CN 1
Olfactory bulb
Olfactory mucosa layer
Optic canal
Optic tract
Optic nerve
Optic chiasm
Which nerves supplu the extra ocular muscles?
- Oculomotor (CN 3)
- Trochlear (CN 4)
- Abducens (CN 6)
Name the extra ocular muscles that CN 3 supplies
- Superior rectus
- Inferior rectus
- Medial rectus
- Inferior oblique
- Levator palpebrae superioris
Name the extra ocular muscles that CN 4 supplies
Superior oblique
Name the extra ocular muscles that CN 6 supplies
Lateral rectus
Midbrain
Pons
CN 12
Medulla
CN 11
CN 10
CN 9
CN 8
CN 7
CN 6
CN 5
CN 4
CN 3
Levator palpebrae superioris
Superior rectus
CN 4
Superior oblique
CN 2
Medial rectus
CN 3
Inferior rectus
Inferior oblique
CN 6
Lateral rectus
Opthalmic Component
Maxillary component
Mandibular component
CN 1
CN 2
CN 3
CN 5
CN 7
CN 8
CN 9
CN 12
CN 12
CN 11
CN 10
CN 6
Explain the general organization of the autonomic pathway
- Each unit of information of the ANS, traveling from the brain to the periphery, utilizes a preganglionic and a postganglionic neuron
- These cells communicate via a synapse in a ganglion outside the CNS
Sympathetic nerves arise from:
levels T1 - L2
Parasympathetic nerves originate from:
Cranial nerves 3, 7, 9, and 10, and sacral levels S2-4
The sypathetic system is also called the
thoracolumbar system
The parasympathetic system is also called the
craniosacral system
When activated the sympathetic outflow acts: (2)
- to shunt blood away from viscera and into skeletal muscles and sweat glands
- on the adrenal medulla causing the release if epinephrine and norephinephrine into circulation evoking a ‘fight or flight’ response
Autonomic nerves are distributed to two general target tissues:
- the body walls, limbs and superfiical head and neck (which maintain homeostasis in these tissues)
- the organ systems within the torso (thorax, abdomen and pelvic cavities) via the splanchnic nerves
Sympathetic preganglionic neurons originate in the __________ qnd exit through the ___________ to join the _______________.
- intermediate horn of the grey matter of the spinal cord (between T1-T2)
- anterior (ventral) root
- spinal nerve
Explain somatotopical arrangement
Axons traveling to the superior parts of the body (head, neck, upper limbs) originate in the superior-most portion of the intermediate horn, while those destined for the thorax exit inferiorly and so on until L1-2 where the pelvic, peritoneal and lower limb axons exit
Sympathetic trunks
- lie on each side of the vertebral column
- consist of interconnected sympathteic ganglia that run from C1-S5
- The ganglia are arranged somatotopically
- originate on intermediate horn
- has a short preganglionic neuron
Superior cervical ganglion
represents C1-4
Middle cervical ganglion
represents C5-6
Inferior cervical ganglion
represents C7-8
Ganglion impar
the most inferior two coccygeal ganglia fuse in midline to form the ganglion impar
Nerves to the skin and blood vessels of the limbs, body walls, and superfiical head and neck, always synapse in the:
sympathetic trunk
Synaptic nerves destined for body walls leave the spinal nerve via the _______, and then enter the ___________
- white ramus communicans
- sympathetic trunk
3 posibilities for the sympathetic nerves destined for body walls
- synapse in the sympathetic trunk ganglion and then exit via the grey ramus communicans to rejoin the spinal nerve
- Travel superiorly to synapse in a higher-level sympathetic ganglion and then leave via the grey ramus communicans to join a spinal nerve
- Travel inferiorly to synapse in the synaptic trunk and then exit via the grey communicans to join the spinal nerve
Splanchnic nerves travel to
organs (viscera)
4 possible pathways that the preganglionic component of the splanchnic nerves must follow:
- Synapse at its own level and go directly to the appriopriate plexus (lungs and some heart innervation)
- Travel superiorly in the trunk to synapse (head and neck and rest of the heart)
- Descend to the inferior lumbar and sacral level to synapse (bladder and reproductive organs)
- Pass through their corresponding sympathetic ganglion and emerge anteromedially as the thoracic and lumbar splanchnic nerves before synapsing in the abdominal ganglia or renal ganglia
Lateral, Intermediate Grey Horn
Sympathetic trunk
White ramus
Spinal nerve
Grey ramus
Solid lines represent _____ and dotted lines represent ________
- Solid line represent sympathetic fibers destined for limbs and body walls
- Dotted lines represent fibers destined for viscera or organs
The pelvic splachnic nerves arise from ______. These send fibers to the _________, ________, and the __________ and also control blood flow to the _________ or ________
- S2-4
- distal GI tract
- the bladder
- the urethra
- the penis
- clitoris
What forms the intramural enteric plexus?
The vagus and pelvic splachnic nerves in the GI tract
Greater splanchnics
Celiac ganglion
Superior mesenteric ganglion
Foregut
Midgut
Sacrum
Hindgut
Hypogastric plexus
Inferior mesenteric ganglion
Lumbar splanchnics
Lesser splanchnics
Sympathetic Innervation of the Eye (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T1
- Superior cervical ganglion
- Intervate with carotid artery to eye and eyelid
Sympathetic Innervation of the Heart (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T1-T4
- Trunk gangli C1-T4
- By cardiac splanchnic nerve to cardiac plexus
Sympathetic Innervation of the Lungs (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T2-T4
- Trunk ganglia T2-T4
- By splanchnic nerves to pulmonary plexus
Sympathetic Innervation of the Foregut (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T5-T9
- Greater splanchnic nerve to celiac ganglion
- Follows branches of celiac trunk to tissue
Sympathetic Innervation of the Midgut (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T10-T11
- Lesser splanchnic nerve to superior mesenteric ganglion
- Follows superior mesenteric artery to midgut
Sympathetic Innervation of the Hindgut (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- L1-L2
- Lumbar splanchnic nerves to inferior mesenteric ganglion
- Follows inferior mesenteric artery to hindgut
Sympathetic Innervation of the Adrenal Medulla (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T5-T9
- Greater splanchnic nerve through celiac ganglion to adrenal
- Synapse directly on adrenal medulla cells
Sympathetic Innervation of the Kidneys (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T12
- Least splanchnic nerve to synapse in renal ganglion
- Follow renal arteries to kidney
Sympathetic Innervation of the Bladder Walls (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T11-L2
- Various ganglia
- Various pathways
Sympathetic Innervation of the Bladder Sphincter Vesicae (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T11-L2
- Inferior mesentery ganglia
- Through aorta chain to anterior hypogastric plexus
Sympathetic Innervation of the Reproductive System (Majority Case) (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T12-L2
- Synapse at same level
- With least splanchnic nerves down preaortic plexuses to inferior hypogastric plexus
Sympathetic Innervation of the Gonads (Pre-Ganglionic Nerve, Ganglion, Post-Ganglionic Nerve)
- T12
- Least splanchnic nerve to synapse in renal ganglion
- Follow gonadal arteries to gonads