The mouth Flashcards
Outline the embryological development of the tooth
1: Bud stage. Line of epithelial cells condenses along jaw margins, invaginate to form dental bud. Surrounded by proliferating mesenchymal cells
2: Cap stage. Bud infolds to form dental cap, neural crest derived mesenchyme forms dental papilla. Remains connected to epithelium via cord of cells, give off-shoots to form more buds.
3: Epithelial cells => ameloblasts => form enamel
4: Mesenchymal cells => odontoblasts =>form dentine
5: Bell stage. Mesenchyme around bud forms vascular dental sac (dental follice). Inner layer forms cementoblasts => cementum. Outer layer form osteoblasts => alveolar bone
6: Enamel organ comprises stellate reticulum plus ameloblasts and outer enamel epithelium
7: Dental sac differentiates into the periodontal ligament
Describe the features of dental anatomy used to age animals
- Number of teeth
- The type of teeth present (incisors, premolar, molar)
- Deciduous vs permanent teeth
- Degree of wear on teeth
- Presence of cups, dental star, Galvayne’s groove
- Spurs or hooks on teeth
Name the salivary glands
- Parotid
- Mandbular
- Zygomatic
- Sub-lingual
- Buccal
- Numerous minor ones (caudal third of tongue, buccal mucosa, labial mucosa and soft palate)
Describe the structure of the salivary glands
- All paired
- Vary in shape and size depending on species
- Empty via large ducts, minor have multiple short ducts
- Made up of multiple salivons
Describe the structure of a basic salivon (top to exit)
- Acinus at top, producing area, made up of mucus and serous cells
- Serous cells: water secretion similar to plasma
- Mucus cells: mucoid secretion
- Plasma cells: around acini, produce IgA
- Intercalated duct: the gathering of the acinus area, secrete HCO3- and absorb Cl-
- Striated duct: exchange of ions, many mitochondria give striated appearance, secrete K+ and HCO3- and absorb Na+
- Secretory ducts: convey saliva to the mouth
Outline the components of saliva and give basic species differences
- Colourless
- Electrolytes
- Proteins
- Amylase
- Desquamated cells from mucosa
- Lymphocytes
Mucin (if mucus secreting gland) - Bicarbonate (buffer)
- Human: acidic
- Most other species alkaline (depends on food eaten)
- Composition modified in strated region
Outline the functions of saliva and describe some species differences
- Wetting agent/lubricant
- Enzyme action
- Buffering action in rumen and to maintain oral pH
- Anti-foaming
- Antibacterial (peroxide based)
- Taste (water soluble components dissolve in saliva)
- Phosphate present as buffer
- Urea for fermentation
- Thermoregulation in dogs and cats
Indicate how and why the electrolyte composition of saliva varies with salivary flow rate and how it compares to plasma
- Primary secretion from acini
- Modified in ducts
- Na reabsorbed, HCO3 and K secreted
- Level of alteration depends on flow
- Greater volume produced, closer to primary secretion concentrations achieved (increased flow rate)
What is the composition of saliva from the mandibular gland in man, ungulates, dogs and cats and rodents? (Serous, mucoid, mixed)
- Mixed in man, ungulates, dogs and cats
- Serous in rodents
What is the composition of saliva from the sub-lingual gland in horses, cattle, pigs, dogs, cats and rodents? (Serous, mucoid, mixed)
- Mixed in horse, cattle, pigs, dogs and cats
- Mucoid in rodents
Describe stimuli to saliva secretion
- Produced in response to neural and hormonal stimuli
- Feeding (taste, smell, composition)
- Reflex
- Can be conditioned
- Balance of sympathetic and parasympathetic
Describe how salivary secretion can be modified by the autonomic nervous system
- Sympathetic:
- Viscous, amylase, protein, increased flow in response to taste, visual and olfactory stimuli
Parasympathetic:
- Water, high volume, continuous basal flow
- Cr. nn VII: mandibular, sublingual, palatine
- Cr. nn IX: parotid (and zygomatic)
Describe the parotid gland
- Ventral to base of ear (base of auricular cartilage in retromandibular position)
- V shaped
- Produces mixed saliva
- Single duct
- Duct runs craniomedially across masseter muscle (dog, sheep) or ventral to it (cattle, horse, pig)
- Duct opens into upper buccal area by maxillary 4th premolar
Describe the zygomatic gland
- Only in dog and cat
- Rostral portion of pterygopalatine fossa on floor of orbit ventral and medial to zygomatic arch and dorsolateral to last maxillary molar tooth
- Duct opens in upper buccal mucosa, opposite upper first molar or caudal to this
- Usually caudal to parotid duct opening
- May have several (~4) minor openings nearby
- Ridge with several small red dots
Describe the mandibular gland
- Caudal and medial to angle of mandible
- Limited by linguofacial vein ventrally and maxillary vein caudally
- Produces mixed saliva
- Capsule shared with monostomatic portion of sublingual salivary gland
- Duct opens at sublingual papilla (caruncle) at base of lingual frenulum
- In 30% of dogs, mandibular and sublingual ducts merge
- Can underogo cystic change
Describe the sublingual gland
- Polystomatic and monostomatic parts
- Mono: long sublingual duct, next to mandibular duct, opens at sublingual caruncle
- Poly: 6-12 lobules with independent short ducts opening sublingually near frenulum
- Mucus mainly, lesser serous component
Describe the minor buccal and palatine glands
- Many small ducs opening locally from gland to the mucosa
Describe the phases of swallowing (deglutition)
- 3 stages: voluntary, involuntary, reflex
- 1: masticated food and saliva formed into bolus, pushed up and back to pharynx
- 2: Swallowing reflex, soft palate elevates. Posterior nares closed, epiglotis covers larynx and trachea, breathing suspended
- 3: Oesophagus dilates, bolus passes, oesophagus closes and epiglottis uncovers trachea, bolus moves down oesophagus to stomach
Briefly outline the function of the tongue (especially in swallowing)
- Muscular organ
- Prehends food, controls food delivery to teeth
- Forms food bolus
- Pushes bolus caudally to be swallowed
- Freely mobile in mammals, variably fixed to floor of mouth in others
- Papillae for taste, molecules dissolve in saliva so can taste
Briefly outline the function of the hyoid apparatus
- Supports larynx from the skull
- Series of bones
Present in many animals, not just mammals - Attachment for muscles
Briefly outline the structure and function of the pharyngeal wall in relation to swallowing
- Made up of striated muscles
- Constriction and shortening: rostral (palatopharyngeus), middle (hyopharyngeus), caudal (thyropharyngeus)
- Insert on roof of pharynx = dorsal and lateral arches allowing passage of food
- Dilation: stylopharyngus caudalis
- Innervated by vagus and glossopharyngeal nerve
Compare swallowing in mammals and reptiles
Mammals: hard palate present, freely mobile tongue, sllows suckling and breathing at same time, can drink by sucking due to 3 seals: lips, tongue against soft palate and soft palate against epiglottis
- Reptiles: secondary hard palate incomplete in many species, no lip seal, minimal chewing, skull types affect prehension
What are the motor nerve supplies in the mouth?
- Masticatory: V3 trigeminal
- Jaw opening: rostral portion is V3, caudal portion is VII
- Swallowing: IX and X
- Intrinsic tongue muscles: XII
What are the sensory nerve supplies to the mouth?
- Touch (GSA):
-> tongue/buccal mucosa: V3
-> teeth: V2 and V3
-> pharynx/larynx: IX/X
Taste (SVA):
-> rostral 2/3 of tongue: VII
-> caudal 1/3 of tongue: IX
-> caudal pharynx and larynx: X
Give the names and numbers of the cranial nerves.
I: Olfactory II: Optic III: oculomotor IV: trochlear V: trigeminal V1: ophthalmic V2: maxillary V3: mandibular VI: abducens VII: facial VIII: vestibulocochlear IX: glossopharyngeal X: vagus XI: Accessory XII: hypoglossal
Describe basic dental anatomy and function relevant to common species
- Found in all bones of the skull across species
- Mammals: incisive, maxilla and mandible
- Snakes: palatine teeth
- Heterodont vs heterodont
- Monophyodont vs polyphyodont vs diphyodont
- Scrodont vs pleurodont vs thecodont
- 4 quadrants of the mouth
- Upper teeth on maxillary bone, close to nasal chamber and maxillary sinus
- Lower teeth on mandible, mandibular canal runs ventrally