the menstrual cycle Flashcards

1
Q

where is GnRh produced

A

the hypothalamus

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2
Q

which gland does the GnRH bind to

A

binds to receptors on the pituitary gland

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3
Q

what does the pituitary gland produce

A

LH and FSH

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4
Q

where do LH and FSH travel to

A

the ovaries via the bloodstream

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5
Q

what does LH and FSH produce when binded to the ovaries

A

production of oestrogen and inhibin

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6
Q

what impact does oestrogen have on the menstrual cycle

A

it helps to regulate it

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7
Q

what does inhibin cause

A

the inhibition of activin which is usually responsible for stimulating GnRH production

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8
Q

What does FSH stimulate

A

the development of ovarian follicles

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9
Q

what does the follicle most sensitive to FSH become

A

the dominant Graafian follicle

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10
Q

What does LH cause the Graafian follicle to change into

A

the corpus luteum

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11
Q

what hormone does the corpus luteum produce

A

progesterone

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12
Q

What does progesterone stimulate

A

the endometrium to become receptive to the implantation of a fertilised ovum

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13
Q

what impact does the increased level of oestrogen, progesterone + inhibin have on the pituitary and hypothalamus

A

negative feedback effect

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14
Q

what does the negative feedback effect on the pituitary and hypothalamus cause

A

decreased production of GnRH, LH and FSH

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15
Q

what does the decreased production of GnRH, LH and FSH cause

A

decreased production of oestrogen and inhibin

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16
Q

what happens to GnRH, FSH and LH in pregnancy

A

they remain inhibited causing menstruation to cease

17
Q

what is the first phase of the menstrual cycle

A

follicular phase

18
Q

what changes occur to FSH levels at the beginning of the menstrual cycle

A

levels of FSH rise causing stimulation of a few ovarian follicles

19
Q

what does the first follicle that fully matures produce

A

large amounts of oestrogen

20
Q

what does oestrogen do to the other follicles

A

inhibits growth

21
Q

what is the follicle that reaches maturity first called

A

Graafian follicle

22
Q

what impact does the increased levels of oestrogen cause on the reproductive organs

A

endometrial thickening, thinning of cervical mucus to allow easier passage of sperm, inhibition of LH production by the pituitary gland

23
Q

when oestrogen levels surpass a threshold level, what do they stimulate

A

the production of LH, resulting in a spike in LH levels around day 12

24
Q

what impact does the rise n LH levels cause on the graafian follicle

A

cause the membrane of the graafian follicle to become thinner

25
Q

when the follicle ruptures what does it release

A

a secondary oocyte

26
Q

what does the secondary oocyte mature into

A

a mature ovum

27
Q

where is the mature ovum released to

A

the peritoneal space and then taken into the fallopian tube fimbriae

28
Q

what is the second phase of the menstrual cycle

A

luteal phase

29
Q

what does the increased level of progesterone result in

A

the endometrium becoming receptive to implantation of the blastocyst