The Limbic System Flashcards

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1
Q

Brief role

A

how do I feel about it

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2
Q

How do we know the function of the limbic system?

A

due to temporal lobe epilepsy (strong distorted emotional states).

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3
Q

what is the limbic system made up of?

A

hypothalamus
amygdala
hippocampus
cingulate gyrus
corpus callosum
thalamus

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4
Q

role of cingulate gyrus

A

learning and memory

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5
Q

role of corpus callosum

A

white matter tract connecting the hemispheres

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6
Q

role of amygdala

A

Stimulation = fear and aggression

Vigilance

Recognising fear in others

Learning about fear (cues)

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7
Q

what clinical conditions are associated with the amygdala?

A

anxiety disorders - hyperactive, hypervigilant (PTSD)

Kluwer-Bucy Syndrome

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8
Q

what is Kluwer-Bucy syndrome?

A

Bilateral lesions (Kluwer-Bucy syndrome – very rare condition resulting in reduced fear/docility, visual agnosia, pica, hyperorality, hypersexuality)

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9
Q

what brain area is the following associated with?

  • Stimulation = fear and aggression
  • Vigilance
  • Recognising fear in others
  • Learning about fear (cues)
A

amygdala

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10
Q

what is the white matter tract connecting the hemispheres called?

A

corpus callosum

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11
Q

what part of the limbic system is associated with learning and memory?

A

cingulate gyrus

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12
Q

role of hippocampus

A
  • Declarative/explicit memory (patient HM)
  • Tells you where you are in space
    o Spatial memory/learning
    o Dorsal/posterior hippocampus
    o Taxi drivers
    o ‘place cells’ – groups of neurons firing when you’re in a certain place
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13
Q

what are place cells?

A

groups of neruons firing when you’re in a certain place

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14
Q

what part of the limbic system does this describe the function of?

Declarative/explicit memory (patient HM)
- Tells you where you are in space
o Spatial memory/learning
o Dorsal/posterior hippocampus
o Taxi drivers
o ‘place cells’ – groups of neurons firing when you’re in a certain place

A

hippocampus

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15
Q

clinical representations of the hippocampus

A

o One of the first sites lost in AD
o Focus for epilepsy
o Active site of neurogenesis (generation of new neurons)
o Anatomically merges with the tail of the caudate nucleus

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16
Q

what does the hippocampus anatomically merge with?

A

the tail of the caudate nucleus

17
Q

role of the fornix

A

connects the hippocampus and hypothalamus

18
Q

what connects the hippocampus and hypothalamus?

A

fornix

19
Q

role of hypothalamus

A
  • Bridges neuro and endocrine
  • Wired into pituitary, brainstem, ANS
  • Thermoregulation, hunger, and thirst, etc
20
Q

what part of the limbic system does this describe?

  • Bridges neuro and endocrine
  • Wired into pituitary, brainstem, ANS
  • Thermoregulation, hunger, and thirst, etc
A

hypothalamus

21
Q

role of thalamus

A
  • Filters sensory info
  • ‘cocktail party effect’
  • The only sensory information it doesn’t receive is olfaction (smell).
22
Q

what part of the limbic system does this describe?

  • Filters sensory info
  • ‘cocktail party effect’
  • The only sensory information it doesn’t receive is olfaction (smell).
A

thalamus

23
Q

what sensory information does the thalamus not receive?

A
  • The only sensory information it doesn’t receive is olfaction (smell).