THE ENDOCRINE SYSTEM Flashcards
The second messenger system of the body.
The Endocrine System
Other term for chemical messages
Hormones
Hormones control several major processes, what are they?
Reproduction, Growth and Development, Mobilization of body defenses, Maintenance of much of Homeostasis, Regulation of metabolism
Where do cells secrete hormones into?
Extracellular Fluid
What transfers hormones to target sites?
Blood
What are the acid-based hormones?
Proteins, Peptides, Amines
Steroids are made of?
Cholesterol
It is made from highly active lipids.
Prostaglandins
True or False. Hormones affect only certain tissues or organs (target cells or organs)
True
True or False. Hormone binding does not influence the working of cell.
False
Hormones can alter cellular activity by __________ and __________ the rate of a normal metabolic process rather than by stimulating of a new one.
Increasing and Decreasing
What maintains the hormone levels in the blood?
Negative Feedback
A stimulus or low hormone levels in the blood triggers the release of (more or less) hormone.
More
Will the hormone release stop if the appropriate level in the blood is reached?
Yes
What forms when hormone enters the cell and bind with the receptor?
Hormone-receptor complex
If the hormone-receptor complex binds to the DNA, what happens?
It triggers transcription of certain genes to mRNA.
True or False. Direct gene activation enables synthesis of a new protein.
True
What mechanism happens when a hormone binds to a receptor on cell’s surface, activating the G-protein?
Second-messenger system
The activated G-protein activates an enzyme that convert ATP to ___________, and is called the second messenger.
cAMP
Three stimuli of Endocrine Glands.
Hormonal stimuli, Humoral stimuli, Neural stimuli
Endocrine glands are activated by other hormones.
Hormonal stimuli
Changing blood levels of certain ions stimulate hormone release.
Humoral stimuli
Capillary blood contains (low or high) concentrations of CA2+, which stimulates secretion of ____________ (PTH).
low, parathyroid hormone
Nerve fibers stimulate hormone release.
Neural stimuli
Preganglionic sympathetic fiber stimulates adrenal medulla cells to secrete ___________________ (epinephrine and norepinephrine).
catecholamines
Major Endocrine Glands
Pineal Gland, hypothalamus, Pituitary gland, Thyroid gland, Parathyroid glands, Thymus gland, Adrenal gland, Pancreas, Ovary, Testis
Compared to a size of a grape that hangs by a stalk from the hypothalamus.
Pituitary Gland
What protects the pituitary gland?
Sphenoid bone
Two functional lobes of pituitary gland
Anterior and Posterior
Composed of glandular tissue.
Anterior Pituitary
Composed of Nervous tissue.
Posterior pituitary
Anterior pituitary has _____ hormones
Six
From six anterior pituitary hormones, ______ affect non-endocrine targets.
Two
From six anterior pituitary hormones, four stimulate other endocrine glands or _________.
Tropic hormones
Characteristics of all anterior pituitary hormones.
Proteins, Act thru second-messenger system, regulated by hormonal stimuli (mostly negative feedback)
The general metabolic hormone
Growth Hormone
Major effects are directed to growth of
skeletal muscles and long bones. Causes amino acids to be built into proteins. Causes fats to be broken down for a source of energy. The one being defined is __________
Growth Hormone
Different hormones of Anterior pituitary gland
Growth hormone, Prolactin, FSH and LH, Thyrotropic hormone, Adrenocorticotropic hormone
Stimulated and maintains milk production; its function for male remains vague.
Prolactin (PRL)
Regulates endocrine activity of the adrenal
cortex.
Adrenocorticotropic hormone (ACTH)