The endocrine system Flashcards

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1
Q

does endocrine system act slowly or quickly

A

slowly

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2
Q

what does endocrine system use

A

chemical messages called hormones

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3
Q

hormones (where produced and carried where)

A

produced in organs callled glands and carried in the blood

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4
Q

neurotransmitter (distributed by what and example)

A

distributed by blood and act as neuro-hormone

ie norepinephrine

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5
Q

endocrine glands

A

secretes hormones in blood

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6
Q

exocrine glands

A

secretes their products (milk or saliva) into a duct for transport to outside

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7
Q

chemical hormones subtype based on chemical structure

A

proteins, amino acid derivatives, steroids

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8
Q

chemical hormones subtypes based on polarity

A

lipophilic (fat-soluble): bind to intracellular receptors, hydrophilic (water-soluble): bind to extracellular receptors

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9
Q

lipophilic hormones

A

1-circulate in the blood attached to a transport protein
2-dissociate from carrier when reaches target cell
3-pass through cell membrane and bind to an intracellular receptor in cytoplasm or nucleus
4-hormone-receptor complex forms to regulate gene expression

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10
Q

hydrophilic hormones

A

1-circulate in blood without transport carrier
2- too large or polar so cant cross cell membrane of target cells
3-bind to extracellular receptor
4-receptors activate kinase enzymes that alter cellular activity
5-these hormones work by producing second messenger (cAMP)

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11
Q

Pituitary gland and consists of what

A

hangs by a stalk from hypothalamus

consists of anterior pituitary (appears glandular) and posterior pituitary (appears fibrous)

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12
Q

posterior pituitary and hormones

A

directly connected to hypothalamus by tract of axons

stores and releases 2 hormones: ADH+oxytocin

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13
Q

oxytocin

A

milk ejection reflex in mammals + uterine contraction during labor + regulates reproductive behavior

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14
Q

ADH

A

stimulates water reabsorbtion by kidney inhibiting urine production

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15
Q

negative feedback in hypothalamus and anterior pituitary

A

hypothalamus-trh-pituitary gland-tsh-thyroid gland-thyroxine-negative feedback-hypothalamus

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16
Q

anterior pituitary and hormones (and where acts)

A

produces 6 essential hormones called tropic hormones: ACTH (adrenal cortex), GH (long bones), PRL (mammary gland), TSH (thyroid), LH (gonads), FSH (gonadsP

17
Q

GH fct and what happens when excess-dificiency child vs adult

A

stimulates growth of muscles and connective tissue cell division so bone elongation

  • gigantism: excessive secretion of growth hormone during childhood (in adults: acromegaly bc cartilage plates are bones)
  • dwarfism
18
Q

thyroid gland and location and hormones

A

shaped like a bow tie below adams apple

-secretes thyroxine (t4), triiodothyronine (t3), calcitonin

19
Q

t4 fct

A

regulates carbohydrate and lipid metabolism

20
Q

hypothyroidism

A

low thyroxine prod

reduced metablism and overweight

21
Q

hyperthyroidism

A
high prod of thyroxine 
high metabolism and weight loss
-protruding eyes
-enlargemnt thyroid gland
-intolerance to heat
22
Q

cause of goiters (growth thyroid gland)

A

iodine dificiency in food or related to hyper-hypothyroidism

23
Q

thyroid gland stimulates uptake of calcium into bones by secreting what?

A

see schma but calcitonin

24
Q

parathyroid glands and hormones

A
4 small glands attached to thyroid
parathyroid hormone (PTH)
25
Q

parathyroid stimulates what

A

Parathyroid stimulates: osteoclasts to dissolve calcium in the bone matrix and release Ca2+ into blood

Stimulates the kidneys to reabsorb Ca2+ from the urine

26
Q

adrenal glands and location and parts

A

above kidneys

  • medulla (inner portion)
  • Cortex (outer portion)
27
Q

Medulla in adrenal glands

A

stimulated by sympathetic division of autonomic nervous system and releases epinephrine and norepinephrine

28
Q

epinephrine and norepinephrine

A

triggers alarm response helping body prepare for extreme efforts + leads to increase in:
heart rate, blood pressure, blood glucose level, blood flow to heart+muscle

29
Q

Cortex in adrenal glands

A

stimulated by anterior pituitary through hormone ACTH and secretes corticosteroids

30
Q

corticosteroids (2 types) and fct

A
  • glucococorticoids (such as cortisol): maintain glucose homeostasis and immune system
  • mineralocorticoids (such as aldosterone): regulate mineral balance by stimulating kidneys to reabsorb Na+ and secrete K+
31
Q

pancreas location and hormones

A

adjacent to stomach and connected to small intetsine by pancreatic duct
Hormones that regulate blood glucose level: insulin and glucagon

32
Q

Insulin in pancreas: secreted by what and stimulates what

A

secreted by beta cells of islets and stimulates cellular uptake of blood glucose and its storage as glycogen in liver and muscle cells or as fait in fat cells

33
Q

glucagon in pancreas: secreted by what and promotes what

A

secreted by alpha cells of islets and promotes hydrolysis of glycogen in liver and fat in adipose

34
Q

2 types of diabetes

A

Type 1: insulin dependant diabetes (lack insulin b cells so daily injections of insulin)

Type 2: non insulin dependant (most and trated by diet and exercise)

35
Q

Gonads fct and hormones

A

produce sex steroids that regulate reproductive development

  • Female hormones: estrogen and progesterone
  • Male hormones: testosterone and its derivatives
36
Q

Pineal gland location and hormone

A

roof of 3rd ventricle of brain and secretes hormone melatonin (regulate biological clock)

37
Q

2 insect hormones

A

-molting by molting hormone (shelding of old exoskeleton) and metamorphosis by low levels of juvenile hormone (radical transformation from the larval to the adult form)