Development Flashcards
steps of early embryogenesis
Fertilization, cleavage, gastrulation, neurulation, embryonic folding and organogenesis (see paper)
3 events fertilization
sperm penetration and membrane fusion (through corona radiata zone and zona pellucida), egg activation, fusion of nuclei
how does sperm penetration happen
acrosome of sperm contains digestive enzymes that drill through corona radiata zone and zona pellucida and then the sperm nucleus enters the eggs cytoplasm
how does egg activation occur
release of Ca2+ where the egg coat is altered so sperm cant go in anymore, increase protein synthesis and rotation of cytoplasm
how does fusion of nuclei occur
sperm and egg nuclei migrate towards and form diploid zygote
cleavage
rapid division of zygote in blastomeres
how are called the external and internal tissues in embryo
external: animal pole
Internal: vegetal pole
how does the hollow ball of cells form (blastocoel)
blastomeres pump Na+ in intracellular spaces (the milk)
cleavage pattern influenced by what
amount of yolk, at the poles there is most cytoplasm which is called the blastodisc and will reslut in embryo being not spherical (recall pic)
if a lot: meroblastic (incomplete) cleavage
If little: holoblastic (complete) cleavage
do mammals have holoblastic or meroblastic cleavage and what does it mean for the shape of the embryo
holoblastic so embryo is spherical
gastrulation
cell mvt in blastula to form 3 germ layers
cell shape changes in gastrulation
invagination (making a tube), Involution (layer of cell moves towards side), delamination
inner cell mass flattens and determines into ? layers
2
Fates of primary germ layers
Ectoderm: epidermis skin, nervous system, sense organs
Endoderm: linning digestive and respiratory tracts, liver, pancreas, thymus, thyroid
Mesoderm: skeleton, muscle, blood vessels, heart, blood, gonads, kidneys, dermis of skin
cell mvt through what gives rise to 3 primary germ layers
primitive streak