Development Flashcards

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1
Q

steps of early embryogenesis

A

Fertilization, cleavage, gastrulation, neurulation, embryonic folding and organogenesis (see paper)

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2
Q

3 events fertilization

A

sperm penetration and membrane fusion (through corona radiata zone and zona pellucida), egg activation, fusion of nuclei

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3
Q

how does sperm penetration happen

A

acrosome of sperm contains digestive enzymes that drill through corona radiata zone and zona pellucida and then the sperm nucleus enters the eggs cytoplasm

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4
Q

how does egg activation occur

A

release of Ca2+ where the egg coat is altered so sperm cant go in anymore, increase protein synthesis and rotation of cytoplasm

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5
Q

how does fusion of nuclei occur

A

sperm and egg nuclei migrate towards and form diploid zygote

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6
Q

cleavage

A

rapid division of zygote in blastomeres

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7
Q

how are called the external and internal tissues in embryo

A

external: animal pole
Internal: vegetal pole

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8
Q

how does the hollow ball of cells form (blastocoel)

A

blastomeres pump Na+ in intracellular spaces (the milk)

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9
Q

cleavage pattern influenced by what

A

amount of yolk, at the poles there is most cytoplasm which is called the blastodisc and will reslut in embryo being not spherical (recall pic)

if a lot: meroblastic (incomplete) cleavage
If little: holoblastic (complete) cleavage

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10
Q

do mammals have holoblastic or meroblastic cleavage and what does it mean for the shape of the embryo

A

holoblastic so embryo is spherical

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11
Q

gastrulation

A

cell mvt in blastula to form 3 germ layers

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12
Q

cell shape changes in gastrulation

A

invagination (making a tube), Involution (layer of cell moves towards side), delamination

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13
Q

inner cell mass flattens and determines into ? layers

A

2

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14
Q

Fates of primary germ layers

A

Ectoderm: epidermis skin, nervous system, sense organs
Endoderm: linning digestive and respiratory tracts, liver, pancreas, thymus, thyroid
Mesoderm: skeleton, muscle, blood vessels, heart, blood, gonads, kidneys, dermis of skin

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15
Q

cell mvt through what gives rise to 3 primary germ layers

A

primitive streak

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16
Q

organogensis and how does it occur

A

formation of organs, interactions with neighboring cells and 3 germ layers (so cell location determines its fate)

17
Q

organogensis in vertebrates

A

begins with neurulation where notochords (little point for support) and neural tube (big point above) develops (as spinal cord)

18
Q

days fertilization to birth

A

266 days

19
Q

4 extraembryonic membranes

A
Amnion (inside amniotic folding)
Choridon (contributes to placenta)
Yolk sac (food source for birds)
Alantois: in mammals blood vessels in umbilical cord, in birds gas exchange
YAAC

order: choridon, amnion, yolk sac, umbilical cord

20
Q

Week 1

A

clevage 30hr after fertilization, 6-7 days after differentiates into blastocyst, implantation

21
Q

Week 2

A

choridon+endometrium=placenta
proximity 2 bloods so gas exchange
gastrulation

22
Q

Week 3

A

Neurulation

23
Q

week 4

A

Organogenesis

24
Q

month 2

A

organogensis continues, small limbs, organs, wheighs 1g,

25
Q

week 9

A

fetus

26
Q

Month 3

A

nervous system, limbs move

27
Q

Month 4

A

bones enlarge

28
Q

when rapid fetal heart beat

A

2nd trimester

29
Q

3rd trimester

A

growth and organ maturation + major nerve tracts

30
Q

positive feedback in birth

A

uterus release prostaglandins=contraction=oxytocin=contraction=oxytocin=contraction…

31
Q

Birth stages

A

cervix relax so dilate
uteirne contraction so delivery
placenta expelled