The Chart Flashcards

1
Q

What are Cold agglutinins?

A

Agglutination of RBC under 37*C

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2
Q

What are Lipemia icterus chylomicrons?

A

Increas Turbidity affects spectrophotomertic reading.

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3
Q

What is Hemolysis?

A

RBCs that have lysed and where not counted.

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4
Q

What is Lysis-resistance RBCs with abnormal Hbs

A

RBCs with Hb S, C, or F may fail to lyse and be counted as WBCs.

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5
Q

What are Microcytosis or schistocytes?

A

The size of RBCs or RBC fragments are at a decreased RBC threshold.

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6
Q

What are Nucleated RBCs, megakaryocyte fragments or micromegakaryoblasts?

A

they are counted as WBC when they should not be.

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7
Q

What are Platelet Clumps?

A

Clumped PLTs that count as WBC

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8
Q

WBC > 100,000/uL

A

Increased turbidity on Hb, WBCs counted with RBC counts.

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9
Q

Leukemia, especially with chemotherapy

A

Fragile WBCs, Fragments Counted as PLTs.

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10
Q

Old specimen.

A

RBCs swell as sample ages,
PLTs swell and degenerate,
WBCs affected by prolonged exposure to ECTA

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11
Q

What parameters are affected with Cold agglutinins?

A

Decreased RBC
Increased MCV, and MCHC
Grainy appearance.

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12
Q

What parameters are affected with Lipemia?

A

Increased HbG, MCH, and MCHC

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13
Q

What parameters are affected with Hemolysis?

A

Decrease RBC and HCT

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14
Q

What parameters are affected with Lysis-resistance RBCs with abnormal HgBs?

A

Increased WBC and HbG

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15
Q

What parameters are affected with Microcytosis or schistocytes?

A

Decreased RBC

Increased WBC

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16
Q

What parameters are affected with Nucleated RBCs, megakaryocyte fragments or micromegakaryoblasts?

A

Increased WBC

17
Q

What parameters are affected with Platelet Clumps?

A

Decrease PLTs

Increased WBCs

18
Q

What parameters are affected with WBC > 100,000/uL?

A

Increased HgB, RBC
Incorrect HCT
Abnormal indices

19
Q

What parameters are affected with Leukemia, especially with chemotherapy?

A

Spurious decreased WBC

Spurious increased PLTs

20
Q

What parameters are affected with Old specimen?

A

Increased MCV, and MPV
Decreased PLT
Automated differential my be incorrect.

21
Q

How do you correct for Cold agglutinins?

A

Warm sample to 37*c and rerun

22
Q

How do you correct for Lipemia?

A

Plasma replacement

23
Q

How do you correct for Hemolysis?

A

Redraw

24
Q

How do you correct for Lysis-resistance RBCs with abnormal HgBs?

A

Manual dilutions and allowing incunation time for lysis

25
Q

How do you correct for Microcytosis or schistocytes?

A

Smear review

26
Q

How do you correct for Nucleated RBCs, megakaryocyte fragments or micromegakaryoblasts?

A

Count nucleated RBCs or micromegakaryoblasts per 100 WBCs and correct.

27
Q

How do you correct for PLT clumps?

A

Redraw in sodium citrate, multiply results by 1.1

28
Q

How do you correct for WBC > 100,000/uL?

A

Bo a Buffy coat and correct.

29
Q

How do you correct for leukemia?

A

Smear review and phase PLT count

30
Q

How do you correct for Old specimen?

A

Establish stability and sample rejection criteria.