the cell the cytoplasm and nucleus Flashcards
nucleolus
blueprints, ribosomal RNA (rRNA) is made here and used for ribosomes→ transcription
Lysosomes
→ recycling, degradaton/digestion
Ribosomes
→ translation, make protein, free floating in the cytoplasm
Peroxisomes
→ fatty acid, metabolism, deformation
Rough ER
→ ribsomes, making things
Smooth ER
→ involved in lipid metabolism, detoxification
4 functions of the plasma membrane
- physical barrier
- selective permeability
- electrochemical gradients
- communication
three types of transport across membranes
- simple diffusion
- channel
- carrier/transporter
simple diffusion
Depending on the nature of the molecule→ small or uncharged- lipophilic (defuse across the membrane)
Channel
large / charged → harder must faciliate transport, Facilitate diffusion, CFTR Cl- channel
4 functions of the ER
- synthesis
- transport
- storage
- detoxification
rough er
synthesizes proteins for secretion
smooth er
lipid synthesis
cell morphology –> 4 types
a. erythroblast
b.eosinophilic leukocyte
c. plasma cell
d. pancreatic acinar cell
erythroblast
cells that make few or no proteins for secretion
- few mito, a golgi, ribosomes and a nucleus
eosinophilic leukocyte
cells that synthesize, segregate, and store various proteins in specific secretory granules
-anti parasitic function
plasma cell
cell that makes antibodies→ active cells, proteins that get secreted
Extensive Rough ER, lots of golgi, mitochondria, don’t see storage vesicles (making cells for immediate use/ products going straight out of the cell)
pancreatic acinar cell
epithelial cells specialized for secretion have distinct polarity
glycogen
storage of glucose in the cell
sequester
storage
devoid of ribosomes
making phospholipids (ER)
steroid hormone synthesis
endocrine gland
golgi apparatus
packaging, sorting and modification
what does not stain well with H+ E? why
golgi because of glycosylation
peroxisome
small, spherical membranous organelle involved in fatty acid metabolism & xenobiotic detoxification
functions of the nucleus (2)
- cellular regulation
- production –> ribosomal subunits
heterochromatin
condensed DNA
no transcription
cell inactive
euchromatin
lighter electron lucent
transcription
active cells
nucleolus
rRNA transcribed
size + number –> active cell
fibrillar centers
templates for ribosomal rna to be produced
dark fibrillar material
where ribosomal RNA is accumulated
prophase
nuclear material condense into chromosomes, nuclear envelope forming and chromosomes condensing
proto-oncogenes
genes involved in cell proliferation and differentiation
4 nuclie components
NPC, nuclear envelope, nucleolus and chromatin