connective tissue Flashcards
connective tissue functions?
transport (blood) artery matrix
immunological defense
mechanical support
connective tissues have cells that can ___
replace damaged cells
fibroblasts
most common ct cell type
hat do fibroblasts produce?
extracellular matrix
macrophages
part of phagocyte system
mast cells
inflammatory cells
plasma cells
produce antibodies
myofibroblasts
form around wounds
what is mast cell secretion triggered by?
re-exposure to certain antigens and allergens
3 types of fibres
- collagen fibres
- reticular fibres
- elastic fibers
reticular fibers
very delicate networks
collagen fibers
extremely strong
key component in ct
elastic fibers
gives resistance
type I collagen
extremely strong
adds mechanical strength
what is the most common collagen type?
type I
where is type I collagen synthesized?
rough ER, secreted by golgi
what type of collagen are reticular fibers
type 3
where are reticular fibers found
in liver, endocrine glands, reticular lamina etc
what makes elastic fibers?
fibroblasts and smooth muscle
what is ground substance made up of?
protein, watery matrix
three classes of ground substance
- glycosaminoglycans
- proteoglycans
- mutliadhesive glycoproteins
glycoprotein
holds fibers together
oligosaccharides
proteoglycans
traps lots of water –> contributes to watery nature of ground substance
laminin
multihesive proteins made by fibroblasts
dense regular connective tissue
regular–> running in same direction
high fibre
dense irregular
dense- high abundance of fibre
irregular- running in different direction
loose irregular
loose - few fibers
irregular- diff direction
reticular tissue
fine, delicate network
type III collagen
mucoid tissue
very loose connective tissue
very little fibre
dominated by ground substance
