The Cell Cycle Flashcards
The Cell Theory
3 Central Principles:
- All organisms are composed of one or more cells
- The cell is the basic unit of life of structure and function of all organisms
- All cells arise form pre-existing cells
The Cell Cycle
series of events which describes the process by which cells divide.
Interphase
- “resting stage” of the cell ycle
- actively metabolizing and synthesizing materials and components needed for cell division
Stages:
A. Gap 1 (G1) Phase
B. S Phase
C. Gap 2 (G2) Phase
Gap 1 Phase (G1)
cells increase in size and synthesize proteins and enzymes needed for DNA replication
*G0 Phase- cells become specialized and are no longer active
S Phase
cells perform DNA replication; creating two sets of DNA
Gap 2 Phase (G2)
Microtubule Synthesis
cells synthesize materials such as microtubules necessary for cell division
Interphase Processes
DNA Replication and Protein Synthesis
A. DNA Replication
- DNA———> DNA
- cell’s DNA makes a duplicate of itself with the aid of various enxymes
- Helicase (unzipper)
- Single Strand Binding Protein (holder of two strands)
- DNA Polymerase (synthesizer)
- Gyrase (reliever)
- Ligase (joins)
- Template Strand (original)
- Leading Strand (continuous)
- Lagging Strand (fragments)
Helicase
“unzips” the two DNA strands
Single Strand Binding Protein
holds the two strands
DNA Polymerase
synthesizes new DNA strand using the original (3’—>5’); producing a complimentary strand (5’——> 3’)
I. DNA Polymerase I -synthesize lagging strand
II. DNA Polymerase III synthesize leading strand
Gyrase
relieves the strain cause from uncoiling
Ligase
joins the pieces of Okazaki Fragments together
Template Strand
original strand
Leading Strand
new strand, synthesized continuously
Lagging Strand
new strand. synthesized in fragments
B. Protein Synthesis
process by which cells synthesize proteins
relies heavily on the different RNA species: mRNA, tRNA, rRNA
Processes: Transcription and Translation
Transcription
- DNA———> RNA
- formation of RNA from DNA that encdoes functional protein
- inside the nucleus