The Adaptive Immune System Flashcards
True or false: adaptive immunity is systemic in action
True
True or false: adaptive immunity does not remember pathogens
False; adaptive memory has a memory and remembers specific pathogens
These are recognized by cells of the adaptive immune system and produce an adaptive immune response
Antigens
ANTIbody GENerator
What do antigens produce?
antibodies
Where are antigens found?
On foreign organisms/particles
On our own cells
What are self antigens and why are they important
Antigens found on our own cells and help to identify what’s foreign and whats not
How is humoral immunity different from cell mediated immunity
Humoral immunity produces response via antibodies; for extracellular pathogens
Cell mediated produces response via cytokines; for intracellular pathogens
Name the three classes of lymphocytes.
NK (natural killer) cells
T (thymus-derived) cells
B (bone marrow-derived) cells
How many antigens does each individual T or B cell respond to?
Only one
CD4 and CD8 receptors can be found on which lymphocyte
T cells
Do immune cells attack self-antigens?
No, except in autoimmune disorders
Describe MHC class I molecules
Found on all nucleated cells
Labels cells when infected to cytotoxic T cells
Describe MHC class II molecules
Found on antigen presenting cells (APCs) /T and B lymphocytes
Communicate antigen-MHC complex to helper T cells
How do antigen presenting cells interact with foreign antibodies?
Engulf and destroy them and display a present antigen on the MHC complex to other immune cells
Name the two main groups of T cells
Helper T cells
Cytotoxic T cells
Helper T cells have CD___ receptors and bind to MHC Class ____ receptors.
CD4
Class II
Cytotoxic T cells have CD___ receptors and bind to MHC Class ___ receptors.
CD8
Class I
Helper T cells produce ______
Cytokines
This type of antigen is presented on Helper T cells
(exogenous or endogenous) ?
Exogenous antigen
What happens when T helper cells secrete cytokines?
- B cell proliferation and antibody production
- Cytotoxic T cell proliferation
What do B cells produce?
Plasma cells
Memory B cells
Difference between memory B cells and memory T cells
B are for humoral response (based in body fluid)
T are for cell mediated response (for infected cells)
