tetracyclines and macrolides

Question 1

doxycycline

Answer 1

MRSA, variable VRE and anaerobes, atypicals; used for lyme disease, MRSA, SSTI and atypical CAP

Question 2

minocycline

Answer 2

MRSA, variable VRE and anaerobes, atypical, used for acne

Question 3

tigecycline

Answer 3

MRSA, VRE, enterobactericiae, anaerobes, atypicals; risk of death and ADRs so only use if really need it

Question 4

tetracycline drugs

Answer 4

doxycycline, minocycline, tigecycline; no activity against pseudomonas or C. diff

Question 5

azithromycin

Answer 5

is a macrolide
- variable against gram positive
- good against gram negative like H flu and moraxella
- good atypical, C trachomatic, and gonorrhea
- no pseuo or enterobactericiae
- used for gonorrhea/non gonorrhea STD, respiratory tract infection