Testicular cancer Flashcards
Which age peaks?
Infancy
25-40 years
60 years
Predisposing congenital defects?
Klinefelters
Cryptorchidism
RFs?
Fam history
Personal history
UNDESCENDED testes
MC types?
Seminoma and non seminoma
Symptoms?
Painless testicular mass
Enlarged testicle
Diagnostic tests?
USG
Blood test
CT
Radical inguinal orchiectomy
Which markers in blood test?
beta hCG, AFP, LDH
What is diagnosis if AFP is elevated?
ALWAYS NON- seminoma!
How to do bioopsy?
NEVER DO BIOPSY
What is only accepted therapeutic and diagnostic procedure?
Radical INGUINAL orchiectomy
Treatment of seminomas?
Radiotherapy
WHat type of chemotx?
Cisplatin, etoposide, w/without Bleomycin
What is BEP regimen?
Bleomycin
Etoposide
Cisplatin
Complications of chemotx?
Bleomycin: Lung fibrosis, triggered by oxygen
Etoposide: secondary leukemia