Lung Cancer Flashcards
Most Common cause of SVCS?
What is diagnosis Based upon?
SCLC
Clinical examination
MC sites of nSCLC metastasis?
BLAB:
Bone
Liver
Adrenals
Brain
MC histology in NSCLC?
Adenocarcinoma
Which sex MC adenocarcinoma NSCLC?
F
What is recurrence rate in early SCLC?
High
Types of NSCLC?
Adenocarcinoma
Squamous cell ca
Large cell ca
What will N2 in Lung cancer mean?
Ipsilateral mediastinal lymph nodes involves
Which “stage” of lung cancer would you have if there’s pleural effusion or pericardial effusion?
Metastatic disease!
Treatment of early stage NSCLC?
SURGERY!!
–> Lobectomy, VATS
When is VATS used as tx in lung ca?
Peripheral tumors less than 6 cm
When do we use adjuvant radiotx in NSCLC?
N2 positive (ipsilateral mediastinal lymph nodes)
R1 positive resection
Narrow margins
Which stages are “early” lung ca stages? (Tx is surgery=
stage IA - IIIA
Which adjucant chemotx is used in early lung cancer?
Cisplatin + vinorelbine
Which stage is n2?
Stage IIIA! (ipsilateral mediastinal lymph node involvement
What is tx in stage IIIB NSCLC?
Which approach do we use?
CHEMORADIOTHERAPY
Sequential is most commonly used (chemo first, radio after)
Differences between Concurrent and sequential chemoradiotherapy?
Concurrent: 2 modalities at the same time. Better outcome, but HIGH toxicity
Sequential: Chemo first, radio after. Worse outcome, but LOW toxicity :)
WHen do we give palliative tx in NSCLC?
In stage IV (Metastatic disease)
Which palliative tx methods in NSCLC?
Cisplatin + pemetrexed
Cisplatin + gemcitabin
Bevacizumab
Which immunotherapy in NSCLC metastases?
Bevacizumab
Are there differences in tx method of squamous vs non-squamous NSCLC?
Non.squamous: Cisplatin + pemetrexed
Squamous: cisplatin + gemcitabin
How does treatment differ in NSCLC and SCLC?
NSCLC: SURGERY + adj. chemo
SCLC: CHEMORADIOTHERAPY
How many percent of SCLC smoked?
95%
Which lung cancer is most chemosensitive?
SCLC
What diagnostic test must always be done in SCLC?
NEUROIMAGING
