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Medicine, oncology > Lung Cancer > Flashcards

Lung Cancer Flashcards

1
Q

Most Common cause of SVCS?

What is diagnosis Based upon?

A

SCLC

Clinical examination

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2
Q

MC sites of nSCLC metastasis?

A

BLAB:

Bone
Liver
Adrenals
Brain

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3
Q

MC histology in NSCLC?

A

Adenocarcinoma

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4
Q

Which sex MC adenocarcinoma NSCLC?

A

F

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5
Q

What is recurrence rate in early SCLC?

A

High

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6
Q

Types of NSCLC?

A

Adenocarcinoma
Squamous cell ca
Large cell ca

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7
Q

What will N2 in Lung cancer mean?

A

Ipsilateral mediastinal lymph nodes involves

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8
Q

Which “stage” of lung cancer would you have if there’s pleural effusion or pericardial effusion?

A

Metastatic disease!

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9
Q

Treatment of early stage NSCLC?

A

SURGERY!!

–> Lobectomy, VATS

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10
Q

When is VATS used as tx in lung ca?

A

Peripheral tumors less than 6 cm

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11
Q

When do we use adjuvant radiotx in NSCLC?

A

N2 positive (ipsilateral mediastinal lymph nodes)
R1 positive resection
Narrow margins

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12
Q

Which stages are “early” lung ca stages? (Tx is surgery=

A

stage IA - IIIA

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13
Q

Which adjucant chemotx is used in early lung cancer?

A

Cisplatin + vinorelbine

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14
Q

Which stage is n2?

A

Stage IIIA! (ipsilateral mediastinal lymph node involvement

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15
Q

What is tx in stage IIIB NSCLC?

Which approach do we use?

A

CHEMORADIOTHERAPY

Sequential is most commonly used (chemo first, radio after)

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16
Q

Differences between Concurrent and sequential chemoradiotherapy?

A

Concurrent: 2 modalities at the same time. Better outcome, but HIGH toxicity

Sequential: Chemo first, radio after. Worse outcome, but LOW toxicity :)

17
Q

WHen do we give palliative tx in NSCLC?

A

In stage IV (Metastatic disease)

18
Q

Which palliative tx methods in NSCLC?

A

Cisplatin + pemetrexed
Cisplatin + gemcitabin
Bevacizumab

19
Q

Which immunotherapy in NSCLC metastases?

A

Bevacizumab

20
Q

Are there differences in tx method of squamous vs non-squamous NSCLC?

A

Non.squamous: Cisplatin + pemetrexed

Squamous: cisplatin + gemcitabin

21
Q

How does treatment differ in NSCLC and SCLC?

A

NSCLC: SURGERY + adj. chemo
SCLC: CHEMORADIOTHERAPY

22
Q

How many percent of SCLC smoked?

A

95%

23
Q

Which lung cancer is most chemosensitive?

A

SCLC

24
Q

What diagnostic test must always be done in SCLC?

A

NEUROIMAGING

25
Q

Which paraneoplastic syndromes in SCLC?

A

Cushings

SIADH

26
Q

Treatment of limited SCLC?

A

CHEMORADIOTHERAPY

+ PCI! (prophylactic cranial irridation)

27
Q

Treatment of extended SCLC?

A

CHEMOTHERAPY

–> cisplatin + etoposide

28
Q

reason for doing PCI in SCLC?

A

Frequent brain metastases

29
Q

Criteria for LIMITED SCLC?

A

Tumor does NOT exceed ONE 1/2 of the chest

Medicine, oncology (15 decks)

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