Head and neck cancer

Question 1

MC histology of head/neck ca?

Answer 1

Squamous

Question 2

MC histology of head/neck ca?

Answer 2

Squamous

Question 3

MC location of head/neck ca?

Answer 3

ORAL cavity > larynx > pharynx

Question 4

Silent areas (symptoms)

Answer 4

Oropharynx

Hypopharynx

Question 5

Red flags?

Answer 5

Asymptomatic neck mass

Symptoms lasting > 2 weeks

Question 6

Grading of H/N ca?

Answer 6

G1: > 75% keratinization
G2: 25-50% keratinization
G3:

Question 7

Grade 3?

Question 8

Does involvement of a single lymph node affect prognosis in ca?

Answer 8

Decrease survival with 50% !!

Question 9

Early stage tx?

Answer 9

Surgery

Radiotherapy

Question 10

In which early stage ca do you do surgery?

Answer 10

Oral ca

Question 11

In which early stage ca do you do radiotx?

Answer 11

Oropharynx, larynx, nasopharynx

Question 12

How would you treat a late stage, resectable tumor?

Answer 12

Surgery with adjuvant chemoradiotx

Question 13

How would you treat a late stage, unresectable tumor?

Answer 13

Concurrent chemoradiotherapy!! (cisplatin)

Question 14

Which biologic agent is used in Head and neck ca?

Mechanism of action?

Answer 14

Cetuximab.

Anti- EGFR

Question 15

In which other ca do you use cetuximab?

Answer 15

Colorectal ca

Question 16

Most common palliative tx of H/N ca?

Answer 16

Cisplatin + 5 FU ( + cetuximab)

Question 17

MC location of head/neck ca?

Answer 17

ORAL cavity > larynx > pharynx

Question 18

Silent areas (symptoms)

Answer 18

Oropharynx

Hypopharynx

Question 19

Red flags?

Answer 19

Asymptomatic neck mass

Symptoms lasting > 2 weeks

Question 20

Grading of H/N ca?

Answer 20

G1: > 75% keratinization
G2: 25-50% keratinization
G3:

Question 21

Grade 3?

Question 22

Does involvement of a single lymph node affect prognosis in ca?

Answer 22

Decrease survival with 50% !!

Question 23

Early stage tx?

Answer 23

Surgery

Radiotherapy

Question 24

In which early stage ca do you do surgery?

Answer 24

Oral ca

Question 25

In which early stage ca do you do radiotx?

Answer 25

Oropharynx, larynx, nasopharynx

Question 26

How would you treat a late stage, resectable tumor?

Answer 26

Surgery with adjuvant chemoradiotx

Question 27

How would you treat a late stage, unresectable tumor?

Answer 27

Concurrent chemoradiotherapy!! (cisplatin)

Question 28

Which biologic agent is used in Head and neck ca?

Mechanism of action?

Answer 28

Cetuximab.

Anti- EGFR

Question 29

In which other ca do you use cetuximab?

Answer 29

Colorectal ca

Question 30

Most common palliative tx of H/N ca?

Answer 30

Cisplatin + 5 FU ( + cetuximab)