test4.2 Flashcards
prolonger repolarization at AV node means what on ekg
inc PR
the class 2 way
class 4s will slow the rise of the action potential
prosthetic valve organisms
staph epidermidis
strep vidridans
heart block tx
CCB, BB (dec AV conduction)
HTN 1st and 2nd line tx with MI comorbidity…stroke comorbidity
MI: BB then add ace/arb, 2. aldosterone agonist
stroke: ace/arb 2. thiazide, cab
nethripic syndrome with reduced compliment levels
bergers, MPGN, lupus
tx arythmie rate with heart failure
digoxin
teat arythmie rate when all else fails
amiodarone
which arrhythmic are most only supraventriclular and which is both both supra ventricular and ventricular
supraventricular= 2,4,digoxin
both=1a,1c,3
A fib tx
2,4
coagulation= warfarin, oral DTI, DXI
(rare 1c)
drugs that dec the metabolism of warfarin
Fuck Dude Throw Me 2CC
Flouconazole
Disulfram
Tri-S
Metronidazole
Cimitidine
Chlorphenicol
what gene metabolizes B blockers
2D6
what metabolized digoxin
p-glycoprotein
also metabolizes, anticancer and HIV
Thinning of fibrosa layer of valve, expansion of spongiosa layer
myxomatosis degredation
stary night
APGN
subendothelial deposits
APGN(beginning), Bergers, MPGN1
sub epithelial deposits
APGN(end, humps), membranous nephropathy
diffuse proliferation and damge to glomerular cell
APGN
is inc in diffuse mesangial sclerosis, type 4 col, fibronectin
diabetic nephropathy
what drugs induce HUS
quinidine
oral contra
ticlodipine
e
gem
cyclosporine
immune complexes deposited in mesangium
bergers
hypocomplimentemia
APGN
MPGN
lupus nephritic
intramesangial deposits and hypercellularity
MPGN1
bloody diahread
HUS( triad +fever+rash)
PKD1 vs PKHD1
PKD1= ADPKD, chorom 16, połycystein
PKHD1=ARPKD, chrom 6, fibrocystein, hepatic fibrosis
VHL vs MET chromosomes
VHL chrom 3 causes hypermethylation
MET trisomy 7
WT1 on chorom
11
three cell types
mucosal fissues and punct hemmorages and ___
chronic cystitis
and mast cells
Vericigut ≠drug
Sildenafil, Verapamil, Diltiazam(CYP3A4 inhibition)
Verapamil ≠drug
Statin, Digoxcin, Dofetilide, Vericigut
Ivabradine ≠drugs
B Block, nonDPN CCB
when not to give Ca CB
with B block, Heart block, HF(causes HF!)
Drugs that exaggerate HF
CCB, NSAID, alcohol
AE for irreversible ADP r inhibitors
TTP
AE for GP2a3b
thrombocytopenia
Quinidine inhibits
CYP 2D6, P-glycoprotein, CYP 3A4
Natiuretic effect
ARNI, Dapaglifozin, Ca block, Dopamine, Vericigut, Fenoldopam
Decreases morbidity and mort
b block, spironolactone, dapagliflozin, aspirin, ANRI, ACEI
antagonists of P2Y12 R
ADP R blocker(INC cAMP >red plate agg.)
stabel angina tx
aspirin, nitrate, bb/ccb
(refractory : ranolazine)
Stroke immediate and management
anti platelet
manage with anticoagulant
a fib
2,4 (maybe 1c if the rest of the heart is healthy)
anticoagulant: warfarin, DTI, DXI
acute supraventricular tachycardia (AVNRT)
adenosine
PCI prep and after management
prep: IV DTI, GP2b3a, heparin
after: aspirin, anti platelet
MI immediate and after management
imm: Morphine, Oxygen, Nitrate, Aspirin
management: BB, ACE, aspirin, statin
diastolic HF
ACE. ANRI, Dapagliflozin, Spironolactone
acute ventricle arythmia
Amiondarone, lidocaine, mexitiline
Prevent v fib in a fib
Amiodarone, 1c, 3, 4, Digoxin, 2
A fib to sinus rhythm
Dofetilide, propofanone
tdp tx
magnesium and bb
onset ischemic attach before and after 4 hours
before: alteplase
after: apixaban
ventricular rate control
BB
ToF tx
proporanolol