Test Three Module 6 Flashcards
What is the Integument?
The protective outer covering on an organism (the rind on a fruit)
What are 3 examples of integument?
- The rind on a fruit
- The exoskeleton on an insect
- The skin on an animal
What is the integument on an insect?
The exoskeleton
The integument is one _____, because it involves many tissues acting together?
one organ
The integument is associated with other organs that are appendages or accessories on the integument such as? (4)
- Hair follicles
- Sebaceous glands
- Sweat glands
- Nails, feathers (on birds)
The combination of the human integument (skin) and its appendages makes up the _____?
Integumentary organ system
The integumentary organ system is _____ of the human body?
largest organ system
what is the largest organ system in the human body?
integumentary organ system
What are the 8 functions of the integumentary system?
- protects underlying tissues and organs
- excretes salts, water, and organic wastes (via glands)
- assists in maintaining body temperture (via adipose insulation to prevent hear loss and evaporation thorugh glands to produce cooling when necessary)
- Synthesizes vitamin D3
- Stores lipids when body takes in more food energy than is needed to power body
- Produces melanin to protect against UV light
- Produces keratin to prevent damage through abrasion and ensure a water-tight seal
- Detects touch, pressure, pain, and temperature
Most of the human integumentary organ system is made up of skin, also known as the _____?
Cutaneous Membrane
The skin (the cutaneous membrane) is made up of how many layers?
2
The skin (cutaneous membrane) is made up of what 2 layers?
The epidermis and Dermis
What is the layer of skin that is the outermost layer to the skin, made up of epithelial tissue?
Epidermis
What is the under layer of skin that is made up of connective tissue?
Dermis
What is the lower layer of the skin?
The dermis
The subcutaneous layer is not part of the skin, but is part of the _____?
Integumentary system
Under the dermis layer is another layer called the?
Hypodermis
The hypodermis is also known as the _____ or the _____?
subcutaneous layer or superficial fascia
The hypodermis is made up of ________?
loose connective tissue proper
The hypodermis is not _____ but is part of the integumentary system?
considered part of the skin or cutaneous layer
______ injections are injections into the hypodermis, below the skin proper?
“Hypodermic”
What layer of skin is the most superficial tissue layer in skin?
Epidermis
The epidermis is largely epithelial tissue and is considered a layer of _____?
Stratified squamous epithelia
A few cells found in the epidermis are not _____ cells but most are?
epithelial
The layers of epidermal epithelial cells are subdivided into sections or _____ based on their physical appearance within the tissue?
strata
Each stratum or layer is made up of layers of mostly _____ cells?
epithelial
Most of the cells in all the strata are ______ cells, but they look slightly different the higher you go in the epidermis?
epithelial
What are the two kinds of epidermis based on how many strata are found?
Thick and thin epidermis
How many strata does thin epidermis/skin have?
Four strata of epithelial cells
How many strata does thick epidermis/skin have?
Five strata of epithelial cells
How thick is thin epidermis/skin?
about 0.08 mm thick (saran wrap)
How thick is thick epidermis/skin?
about 0.5 mm thick (paper towel) (6x thick than thin)
Thin epidermis is found?
in most parts of the body
Thick epidermis is found?
on palms and soles of feet
Thin epidermis often dips to form _____ ?
hair follicles
Thick epidermis do not include _____ like thin epidermis?
hair follicles
Skin is epidermis and dermis together, and they sit on top of the ______?
hypodermis
And, both “thick” and “thin” skin have much wider dermis and hypodermis layers than ______?
epidermis
What is the 4 strata in thin skin/epidermis?
Stratum corneum
Stratum granulosum
Stratum spinosum
Stratum germinativum
What are the 5 strata found in thick skin/epidermis?
Stratum corneum Stratum lucidum Stratum granulosum Stratum spinosum Stratum germinativum
What is the most superficial strata?
Stratum corneum
What is the extra strata not found in thin epidermis/skin?
Stratum lucidum
What is the deepest stratum?
Stratum germinativum
What contributes most to the extra thickness of thick epidermis?
More layers in startum corneum
The extra thickness of thick epidermis is more due to extra large size of one of the most outer stratum that is called _____, rather having an additional (fifth) stratum (which is not very thick) over thin epidermis?
Stratum corneum
The _____ is the innermost/deepest stratum in epidermis (one layer thick, usually) and contains mostly basal cells?
Stratum germinativum
About ___% of the cells in the stratum germinativum are basal cells?
70%
____ are the epithelial stem cells found in the epidermis?
Basal cells
What is the name of the stem cells of the epidermis?
Basal cells
As adult stem cells, ______ divide into two daughter cells, one of which remains a stem cell, and the other of which specializes?
basal cells
When basal cells in stratum germinativum divide, _____ cells are always created on top of bottom layer of cells, pushing all other layers up. They divide into top and bottom daughter cells, not left and right?
daughter
The lower daughter cell remains a _____ & the upper daughter cell usually becomes a ______ like most of the other epithelial cells?
stem cell and keratinocyte
Where do epidermal cells germinate?
The stratum germinativum
Basal cells in the stratum germinativum are more cuboidal than squameous, but epidermis is considered _____ because the most apical (highest) cells are very squamous?
Squamous stratified epithelium
What do you look at to determine the shape of the stratified epithelium?
Most apical shape
As the most basolateral layer of cells in an epithelium, basal cells in stratum germinativum are attached via cell-adhesion proteins to the _______ protein fibers below them, which in turn is attached to the connective tissue fibers of the dermis layer below it?
basement membrane
The stratum germinativum is _____ where it attaches to the basement membrane, which blends into the connective tissue of the ______?
wavy and dermis
Finger projections of epidermis “down” into dermis are called _____?
epidermal ridges
Finger projections of dermis “up” into epidermis are called _____?
dermal papillae
The _____ and ______ projections serve to increase the area of attachment between the two layers, allowing for more cell adhesion proteins?
epidermal ridges and dermal papillae
The more cell adhesion proteins means the _____ the connection?
stronger
Most of the basal cells in the stratum germinativum give rise to daughter cells that develop into _____ cells (“skin cells”), but some develop into another specialised cell called a Merkel cell?
keratinocyte
Where do merkel cells stay?
In the stratum germinativum and they are not pushed to the higher layer
About 5% of the cells in the stratu germinativum are _____ cells?
merkel cells
What cells are most abundant in touch sensitive areas like finger tips?
merkel cells
How do merkel cells allow you to relay info about touch?
Merkel cells are connected to neurons and are involved in relaying information about touch
What is is it called when merkel cells are involved in relaying info about touch?
mechanosensation
The neurons attached to merkel cells com up through the _____ and dont enter the _____?
dermis and epidermis
What is the only mechanoreceptors (touch receptors) in the epidermis?
Merkel cells
About 25% of the cells in the stratum germanitivum are _____?
melanocytes
What cells are specialized cells that produce amounts of the pigment molecule melanin?
Melanocytes
_____ cells are scattered throughout stratum germinativum, but they have cell extensions that reach into higher /more superficial strata?
melanocytes
melanocytes synthesis the pigment melanin, a yellow-brown or black pigment in special organelles called _____?
melansomes
Melanocytes do not arise from basal cells?
Melanocytes
_____ are specialized nervous system cells that move into the epidermis during embryonic development?
Melanocytes
What are the 3 types of cells in the deepest/lowest stratum of the epidermis?
- basal cells
- merkel cells
- melanocytes
____ are the adult stem cells?
basal cells
_____ are the cells that detect pressure/touch and send signals to the nervous system?
merkel cells
_____ are the cells that produce the pigment melanin and distribute it to cells in the higher strata of the epidermis?
melanocytes
Most of the cells in the epidermis are _____?
keratinocytes
Most cells that arise from division of basal cells in stratum germinativum will develop into _____ cells?
keratinocytes
_____ are mature “skin cells” that dominates the epidermis, arising from the specialization of a basal cell as it is pushed up into higher strata of the epidermis?
keratinocytes
The highest strata of the epidermis contains dead _____?
keratinocytes
The lower strata contain living ______?
keratinocytes
What are mature epidermal cells called?
keratinocytes
The outer layer of the skin is the ______ stratum of the epidermis, which are dead packets of protein fibers?
highest
The most superficial layer of the epidermis is the ______, containing dead, tightly connected, membrane-bound packages of keratin and keratohyalin?
stratum corneum
The deepest layer of the epidermis is _____, containing epithelial stem cells, mostly (plus Merkel cells and melanocytes) ?
stratum germinativum
_____ cells are a type of immune white blood cell that has left the blood and moved into the middle strata of the epidermis?
Langerhans
_____ cells do not combat or destroy foreign invaders, like other immune cells?
Langerhans
_____ cells engulf bits of everything that comes near them?
Langerhans
_____ cells have numerous projections to increase their reach to spots in the epidermis around them?
Langerhans
With epithelia what are the 5 main cell types?
basal cells keratinocytes melanocytes merkel cells langerhans cells
The _____ is the most superficial layer of the epidermis, making up the exposed surface of the skin?
stratum corneum