Test II: Body Structures-Neural and Epithelial Tissue Flashcards
Collections of cell and cell products that perform specific, limited functions
Tissue
Hierarchy of body structures
Atoms Molecules Cells Tissues Organs Organ systems Organism
4 types of tissue
- Epithelial tissue
- Connective tissue
- Muscle tissue
- Neural tissue
Functions of epithelial tissue
- covers exposed surfaces
- lines internal passageways
- forms glands
Functions of connective tissue
- fills internal spaces
- supports other tissues
- transports materials
- stores energy
Functions of muscle tissue
- specialized for contraction
- skeletal muscle, heart muscle, and walls of hollow organs
Functions of neural tissue (nervous/nerve tissue)
- Carries electrical signals from one part of the body to another
- specialized for conducting electrical pulses
- rapidly senses internal or external environment
- processes information ad controls responses
Where is the neural tissue concentrated?
The central nervous system (brain and spinal cord)
Two types of neural cells
Neurons and neuroglia
Type of neural cell that perform electrical communication
Neurons/nerve cells
Type of neural cell that are supporting cells which repair and supply nutrients to neurons
Neuroglia
Functions of neuroglia
- maintain physical structure of tissues
- repair tissue framework after injury
- perform phagocytosis
- provide nutrients to neurons
- regulate the composition of the interstitial fluid surrounding neurons
Part of neuron that conducts information to other cells
Axon
Part of neuron that are contacted by other neurons
Dendrites
Unequal charge across the plasma membrane
Transmembrane potential
How are information transmitted?
Within each and between neurons
Created when charges are separated
Potential difference
What is the range of the resting potential?
-10 mV to -100mV depending on cell type
70mV different between the inside and outside the cell
Resting potential
Electrical charge across the membrane
membrane potential
Exchanges three Na+ ions for 2 K+ ions
Sodium-potassium pump
How does the resting potential exists?
Ions are concentrated on different sides of membrane:
- Na+ and Cl- outside the cell
- K+ and organic anions inside the cell
How is the resting potential maintained?
Na+ ions are actively transported (this uses energy)
Rapid depolarization of the membrane
Action potential (neuronal firing)
Rapid depolarization
- when partial depolarization reaches the activation threshold, voltage-gated ion channels open
- sodium ions rush in
- the membrane potential channels from -70mV to +40mV
Process of action potential
It starts at the axon hillock and passes quickly along the axon. The membrane is quickly repolarized to allow subsequent firing.
Repolarization
- sodium ion channels close and become refractory
- depolarization triggers opening of voltage-gated potassium ion channels
- K+ ions rush out of the cell, repolarizing and then hyperpolarizing the membrane
Process of resuming the resting potential
- potassium channels close
- repolarization resets sodium ion channels
- ions diffuse away from the area
- sodium-potassium transporter maintains polarization
- the membrane is now ready to “fire” again
Layers of cells covering internal or externals surfaces
Epithelia
Course of the action potential (all-or none)
- The action potential begins with a partial depolarization (e.gb from voting of another neuron)
- When the excitation threshold is reached there is a sudden depolarization.
- This is followed rapidly by repolarization and a brief hyperpolarization.
- There is a refractory period immediately at the action potential where no depolarization can occur.
Structures that produce secretions
Glands
Characteristics of epithelia
- cellularity (cell junction)
- polarity (apical and basal surfaces)
- attachment (basement membrane or basal lamina)
- avascularity
- regeneration
Functions of epithelial tissue
- Provide physical protection
- Control permeability
- Provide sensation
- Produce specialized secretions (glandular epithelium)
Specializations of epithelial cells
- Move fluids over the epithelium (protection)
- Move fluids through the epithelium (permeability)
- Produce secretions (protection and messengers)
Polarity of epithelial tissue
- Apical surface (microvilli and cilia)
2. Basolateral surface
Apical surface that increases absorption or secretion
Microvilli
Apical surface that moves fluid
Cilia/ciliated epithelium
How is integrity of epithelial maintained?
- Intercellular connections
- Attachment to the basement membrane
- Epithelial maintenance
Intercellular connections
- CAMs (cell adhesion molecules) - transmembrane proteins
- intercellular cement - proteoglycan
- hyaluronan (hyaluronic acid) - glycosaminoglycans
Form bonds with other cells
Cell junctions
Types of cell junctions
- Tight junctions
- Gap junctions
- Desmosomes
Junction that provides connection between plasma membranes, prevents passage of water and isolates wastes in the lumen. Its adhesion belt attaches to terminal web.
Tight junction
Junction that allow rapid communications, held together by channel proteins (junctional proteins, connexons), allows ions to pass and coordinate contractions in heart muscle.
Gap junctions
Junction that has dense areas and intercellular cement.
Desmosomes
Types of desmosomes
Spot desmosomes
Hemidesmosomes
Type of desmosomes that tie cells together and allow bending and twisting
Spot desmosome
Type of desmosome that attaches cells to the basal lamina
Hemidesmosome
Type of squamous epithelia
Simple squamous epithelium
Mesothelium
Endothelium
Type of squamous epithelial whose function is absorption and diffusion
Simple squamous epithelia
Squamous epithelial that lines body cavities
Mesothelia
Squamous epithelial that lines heart and blood vessels
Endothelium
Classification of epithelia
Squamous epithelia
Glandular epithelia
The only unicellular exocrine glands that are scattered among epithelia, ex. intestinal lining
Mucous (goblet) cells
Structural classification of exocrine glands
Simple tubular (ex: intestinal glands)
Simple could tubular (merocrine sweat glands)
Simple branched tubular (gastric glands, mucous glands of esophagus, tongue, duodenum)
Simple alveolar (acinar)
Simple branched alveolar (sebaceous glands)
Type of compound glands
Compound tubular
Compound alveolar (acinar)
Compound tubuloalveolar
Examples of compound tubular
Mucous glands (in mouth)
Bulbo-urethral glands (in male reproductive system)
Testes (seminiferous tubules)
Ex. of compound alveolar (Acinar)
mammary glands
Ex. of compound tubuloalveolar
salivary glands
glands of respiratory passages
pancreas