TEST II Flashcards

MULTIPLE CHOICES

1
Q

what clotting factors plays a role in clot formation in vitro, but not in vivo?

A

XIIa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What initiates in vivo coagulation by activation of factor VII

A

The tissue factor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is the charactristic of vitamin k

A

It is required for carboxylation of glutamate residues of some coagulation factors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

which protein is the primary inhibitor of the fibrinolytic system

A

alpha 2- antiplasmin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Thrombocytopenia may be associated with

A

Hyperslenism

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Asprin prevents platelet aggregation by inhibiting the action of which enzyme?

A

Cyclo-Oxygenase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Normal platelet adhesion depends upon what

A

Glycoprotein lb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Bernard-soulier syndrome is associated with

A

Thrombocytopenia giant platelets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

several hours after birth, a baby boy develops petechiae and purpura and a hemorrhagic diathesis. The platelet count is 18 x 109/L. What is the most likely explanation for the low platelet count?

Petechiae are pinpoint, round spots that form on the skin due to bleeding. They can appear as small red or purple patches just under the skin.
Purpura are red, purple, or brown blood spots that appear on your skin

A

Neonatal alloimmune thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What prevent platelet aggregation

A
  1. Prostacyclin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what plasma protein is essential for platelet adhesion

A

vWF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Platelet aggregation refers to

A

Platelets stickig together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

proteins present in both plasma and alpha graules exclude

A

plasminogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Clinical profiling instruments can generate one of the following parameters which manual methods cannot determine in blood samples

A

mean platelet volume

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

The normal peripheral platelet count is

A

150-400 x10^9/L

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Platelet agonists that activate platelets exlude

A

Thromboxane A2

17
Q

Platelets adhere to fibrillar vWF through

A

GP IB/IX/V

18
Q

The following are tissue factor bearing cells except

A

all of the cells answers above

19
Q

Coagulation factors VIII circulatesbound to

A

vWF

20
Q

What coagulation plasma protein should be assayed when platelets fail to aggregate properly

A

vWF