Test 1. Important differences

Question 1

one important difference between
chronic lymphocytic leukemia and small lymphocytic lymphoma

Answer 1

Chronic lymphocycytic leukemia are present in a peripheral blood and bone marrow while small lymphocytic lymphoma is present in lymoh nodes and other lymphoid organs

Question 2

one important difference between the Pre-germinal center CLL and post-germinal center CLL (2 marks)

Answer 2

Pregeminal center of CLL there is no mutation of VH gene and there is trisomy 12 while in post germinal center there is mutation of VH gene and deletion of chromosome 13q14

Question 3

one important difference between Small lymphoblast and large lymphoblast (2 marks)

Answer 3

small lymphocytes are involved in antibody production while large lymphoblasts are involved in differentiation process to produce more specialized and functional cells such as mature lymphocytes

Question 3

one important difference between Blast count in Blastic crisis and metamorphosis (acceleration) phase of CML (2
narks)

Answer 3

Blast count in blastic crisis os greater than or equal to 20% while in acceralation phase is 10-19

Question 4

Whta is the important difference between Accelerated phase and Blastic phase of CML (2 marks)

Answer 4

Accelerated phase there is 10 - 19 of blast while in blastic phase there is greater than or equal to 20% of blast.